TPDB

3D PDB MODEL

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TPDB ID TPDB15006

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 121-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.

Sequence

SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKADPC

FASTA

>TPDB15006|Antibacterial|length=121
SLFELGKMILQETGKNPAKSYGAYGCNCGVLGRGKPKDATDRCCYVHKCCYKKLTGCNPKKDRYSYSWKDKTIVCGENNPCLKELCECDKAVAICLRENLGTYNKKYRYHLKPFCKKADPC

Formula C598H950N168O172S15

Absent Amino Acids

Common Amino Acids K

Mass 13726.04

PI 8.87

Basic Residues 26

Acidic Residues 12

Hydrophobic Residues 36

Net Charge +12

Boman Index 28.39

Hydrophobicity -0.697

Aliphatic Index 56.45

Half Life

Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 19785

Absorbance 280nm 144.14

Polar Residues 40

number

6

A

5

R

7

N

6

D

14

C

6

E

1

Q

10

G

2

H

3

I

10

L

19

K

1

M

2

F

6

P

4

S

5

T

1

W

9

Y

4

V

Amino Acid Distribution

A: 6 R: 5 N: 7 D: 6 C: 14 E: 6 Q: 1 G: 10 H: 2 I: 3 L: 10 K: 19 M: 1 F: 2 P: 6 S: 4 T: 5 W: 1 Y: 9 V: 4

Length

121

Formula

C598H950N168O172S15

Mass

13726.04

PI

8.87

Net Charge

+12

Boman Index

28.39

Hydrophobicity

-0.697

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.