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Peptide record

TPDB14991

Antibacterial Anticancer Antifungal Antiparasitic standard
51 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB14991
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia Antifp Antifungipept
standard
No
A 51-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
SGRGKTGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYAHRVGAGAPVYL
Physicochemical Analysis
C236H398N86O61
DCEIMW
G
5416.30
12.63
15
0
18
+13
9.85
-0.680
67.06
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
2980
55.02
9
Residue Composition
number
7
A
8
R
1
N
0
D
0
C
0
E
1
Q
9
G
2
H
0
I
4
L
5
K
0
M
1
F
2
P
3
S
2
T
0
W
2
Y
4
V
Amino Acid Distribution
A: 7 R: 8 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 9 H: 2 I: 0 L: 4 K: 5 M: 0 F: 1 P: 2 S: 3 T: 2 W: 0 Y: 2 V: 4
Chemical Descriptors
51
C236H398N86O61
5416.30
12.63
+13
9.85
-0.680
Evidence Records 36 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.3-2.5 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against Gram+ B. subtilis (MIC 1.3-2.5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. au
Evidence 2 Activity

Activity

MIC
Antibacterial
40-80 µM

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP

Other

Active against Gram+ B. subtilis (MIC 1.3-2.5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L.
Evidence 3 Activity

Activity

MIC
Antibacterial
40-80 µM

Target

E. avicum

Source & Reference

dbAMP DRAMP

Other

m+ B. subtilis (MIC 1.3-2.5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM)
Evidence 4 Activity

Activity

MIC
Antibacterial
40-80 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 u
Evidence 5 Activity

Activity

MIC
Antibacterial
0.6-1.2 µM

Target

L. corenyformis

Source & Reference

dbAMP DRAMP

Other

C>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 u
Evidence 6 Activity

Activity

MIC
Antibacterial
0.6-1.2 µM

Target

L. ivanovii

Source & Reference

dbAMP DRAMP

Other

M), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK2
Evidence 7 Activity

Activity

MIC
Antibacterial
10 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP

Other

S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM)
Evidence 8 Activity

Activity

MIC
Antibacterial
20 µM

Target

A. salmonicida

Source & Reference

dbAMP DRAMP

Other

yformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM),
Evidence 9 Activity

Activity

MIC
Antibacterial
2.5-5 µM

Target

Escherichia coli ATCC 14763 or pHK22 or DH5alpha

Source & Reference

dbAMP DRAMP

Other

ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM), Pseudomonas sp. (MIC 20-40 uM), S. soneii (MIC 10-20 uM
Evidence 10 Activity

Activity

MIC
Antibacterial
20-40 µM

Target

P. flourescences

Source & Reference

dbAMP DRAMP

Other

Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM), Pseudomonas sp. (MIC 20-40 uM), S. soneii (MIC 10-20 uM), V. anguillarum (MIC 2.5-10 uM,
Evidence 11 Activity

Activity

MIC
Antibacterial
10-20 µM

Target

S. soneii

Source & Reference

dbAMP DRAMP

Other

DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM), Pseudomonas sp. (MIC 20-40 uM), S. soneii (MIC 10-20 uM), V. anguillarum (MIC 2.5-10 uM, HI-644 strain MIC>80 uM), and V. salmonicida (MIC 10-20 u
Evidence 12 Activity

Activity

MIC
Antibacterial
10-20 µM

Target

V. salmonicida

Source & Reference

dbAMP DRAMP

Other

), S. soneii (MIC 10-20 uM), V. anguillarum (MIC 2.5-10 uM, HI-644 strain MIC>80 uM), and V. salmonicida (MIC 10-20 uM).
Evidence 13 Activity

Activity

MIC
Antifungal
1.3-2.5 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against Gram+ B. subtilis (MIC 1.3-2.5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. au
Evidence 14 Activity

Activity

MIC
Antifungal
40-80 µM

Target

Enterococcus faecalis

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against Gram+ B. subtilis (MIC 1.3-2.5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L.
Evidence 15 Activity

Activity

MIC
Antifungal
40-80 µM

Target

E. avicum

Source & Reference

dbAMP DRAMP Antifungipept

Other

m+ B. subtilis (MIC 1.3-2.5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM)
Evidence 16 Activity

Activity

MIC
Antifungal
40-80 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP Antifungipept

Other

5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 u
Evidence 17 Activity

Activity

MIC
Antifungal
0.6-1.2 µM

Target

L. corenyformis

Source & Reference

dbAMP DRAMP Antifungipept

Other

C>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 u
Evidence 18 Activity

Activity

MIC
Antifungal
0.6-1.2 µM

Target

L. ivanovii

Source & Reference

dbAMP DRAMP Antifungipept

Other

M), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK2
Evidence 19 Activity

Activity

MIC
Antifungal
10 µM

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP Antifungipept

Other

S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM)
Evidence 20 Activity

Activity

MIC
Antifungal
20 µM

Target

A. salmonicida

Source & Reference

dbAMP DRAMP Antifungipept

Other

yformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM),
Evidence 21 Activity

Activity

MIC
Antifungal
2.5-5 µM

Target

Escherichia coli ATCC 14763 or pHK22 or DH5alpha

Source & Reference

dbAMP DRAMP Antifungipept

Other

ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM), Pseudomonas sp. (MIC 20-40 uM), S. soneii (MIC 10-20 uM
Evidence 22 Activity

Activity

MIC
Antifungal
20-40 µM

Target

P. flourescences

Source & Reference

dbAMP DRAMP Antifungipept

Other

Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM), Pseudomonas sp. (MIC 20-40 uM), S. soneii (MIC 10-20 uM), V. anguillarum (MIC 2.5-10 uM,
Evidence 23 Activity

Activity

MIC
Antifungal
10-20 µM

Target

S. soneii

Source & Reference

dbAMP DRAMP Antifungipept

Other

DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM), Pseudomonas sp. (MIC 20-40 uM), S. soneii (MIC 10-20 uM), V. anguillarum (MIC 2.5-10 uM, HI-644 strain MIC>80 uM), and V. salmonicida (MIC 10-20 u
Evidence 24 Activity

Activity

MIC
Antifungal
10-20 µM

Target

V. salmonicida

Source & Reference

dbAMP DRAMP Antifungipept

Other

), S. soneii (MIC 10-20 uM), V. anguillarum (MIC 2.5-10 uM, HI-644 strain MIC>80 uM), and V. salmonicida (MIC 10-20 uM).
Evidence 25 Activity

Activity

MIC
Antiparasitic
1.3-2.5 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against Gram+ B. subtilis (MIC 1.3-2.5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. au
Evidence 26 Activity

Activity

MIC
Antiparasitic
40-80 µM

Target

Enterococcus faecalis

Source & Reference

DRAMP

Other

Active against Gram+ B. subtilis (MIC 1.3-2.5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L.
Evidence 27 Activity

Activity

MIC
Antiparasitic
40-80 µM

Target

E. avicum

Source & Reference

DRAMP

Other

m+ B. subtilis (MIC 1.3-2.5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM)
Evidence 28 Activity

Activity

MIC
Antiparasitic
40-80 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

5 uM), B-thuringiensis (MIC>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 u
Evidence 29 Activity

Activity

MIC
Antiparasitic
0.6-1.2 µM

Target

L. corenyformis

Source & Reference

DRAMP

Other

C>80 uM), E. faecalis (MIC 40-80 uM), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 u
Evidence 30 Activity

Activity

MIC
Antiparasitic
0.6-1.2 µM

Target

L. ivanovii

Source & Reference

DRAMP

Other

M), E. avicum (MIC 40-80 uM), S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK2
Evidence 31 Activity

Activity

MIC
Antiparasitic
10 µM

Target

Staphylococcus epidermidis

Source & Reference

DRAMP

Other

S. aureus (MIC 40-80 uM), L. corenyformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM)
Evidence 32 Activity

Activity

MIC
Antiparasitic
20 µM

Target

A. salmonicida

Source & Reference

DRAMP

Other

yformis (MIC 0.6-1.2 uM), L. ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM),
Evidence 33 Activity

Activity

MIC
Antiparasitic
2.5-5 µM

Target

Escherichia coli ATCC 14763 or pHK22 or DH5alpha

Source & Reference

DRAMP

Other

ivanovii (MIC 0.6-1.2 uM), S. epidermidis (MIC 10 uM), Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM), Pseudomonas sp. (MIC 20-40 uM), S. soneii (MIC 10-20 uM
Evidence 34 Activity

Activity

MIC
Antiparasitic
20-40 µM

Target

P. flourescences

Source & Reference

DRAMP

Other

Gram- A. salmonicida (MIC 20 uM), E. coli ATCC 14763 or pHK22 or DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM), Pseudomonas sp. (MIC 20-40 uM), S. soneii (MIC 10-20 uM), V. anguillarum (MIC 2.5-10 uM,
Evidence 35 Activity

Activity

MIC
Antiparasitic
10-20 µM

Target

S. soneii

Source & Reference

DRAMP

Other

DH5alpha (MIC 2.5-5 uM), P. flourescences (MIC 20-40 uM), Pseudomonas sp. (MIC 20-40 uM), S. soneii (MIC 10-20 uM), V. anguillarum (MIC 2.5-10 uM, HI-644 strain MIC>80 uM), and V. salmonicida (MIC 10-20 u
Evidence 36 Activity

Activity

MIC
Antiparasitic
10-20 µM

Target

V. salmonicida

Source & Reference

DRAMP

Other

), S. soneii (MIC 10-20 uM), V. anguillarum (MIC 2.5-10 uM, HI-644 strain MIC>80 uM), and V. salmonicida (MIC 10-20 uM).