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Peptide record

TPDB14952

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
60 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB14952
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP DRAMP Peptipedia AFP-GFuse Antifp Antifungipept
standard
No
A 60-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
RRIRPRPPRLPRPRPRPLPFPRPGPRPIPRPLPFPRPGPRPIPRPLPFPRPGPRPIPRPL
Physicochemical Analysis
C329H537N111O61
ANDCEQHKMSTWYV
P
7023.59
13.60
17
0
12
+17
18.97
-1.285
58.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
17
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
4
I
5
L
0
K
0
M
3
F
28
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 17 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 4 L: 5 K: 0 M: 0 F: 3 P: 28 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
60
C329H537N111O61
7023.59
13.60
+17
18.97
-1.285
Evidence Records 32 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1 µM

Target

Escherichia coli ATCC 25922 or ML-35

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against E. coli ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM)
Evidence 2 Activity

Activity

MIC
Antibacterial
1 µM

Target

S. enterica serovar Typhimurium ATCC 14028

Source & Reference

dbAMP DRAMP

Other

active against E. coli ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S.
Evidence 3 Activity

Activity

MIC
Antibacterial
1 µM

Target

S. marcescens ATCC8100

Source & Reference

dbAMP DRAMP

Other

li ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or
Evidence 4 Activity

Activity

MIC
Antibacterial
>128 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP DRAMP

Other

S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. p
Evidence 5 Activity

Activity

MIC
Antibacterial
12-25 µg/mL

Target

S. enterica serovar typhimurium LT2 or ATCC 14028

Source & Reference

dbAMP DRAMP

Other

uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeru
Evidence 6 Activity

Activity

MIC
Antibacterial
12 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

dbAMP DRAMP

Other

uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller
Evidence 7 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

Enterobacter cloacae ATCC 13047

Source & Reference

dbAMP DRAMP

Other

typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller-Hinton broth)(provided by Chunfeng Wa
Evidence 8 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

Pseudomonas aeruginosa ATCC 7700

Source & Reference

dbAMP DRAMP

Other

ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller-Hinton broth)(provided by Chunfeng Wang).
Evidence 9 Activity

Activity

MIC
Antifungal
1 µM

Target

Escherichia coli ATCC 25922 or ML-35

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against E. coli ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM)
Evidence 10 Activity

Activity

MIC
Antifungal
1 µM

Target

S. enterica serovar Typhimurium ATCC 14028

Source & Reference

dbAMP DRAMP Antifungipept

Other

active against E. coli ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S.
Evidence 11 Activity

Activity

MIC
Antifungal
1 µM

Target

S. marcescens ATCC8100

Source & Reference

dbAMP DRAMP Antifungipept

Other

li ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or
Evidence 12 Activity

Activity

MIC
Antifungal
>128 µM

Target

S.aureus ATCC 25923

Source & Reference

dbAMP DRAMP Antifungipept

Other

S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. p
Evidence 13 Activity

Activity

MIC
Antifungal
12-25 µg/mL

Target

S. enterica serovar typhimurium LT2 or ATCC 14028

Source & Reference

dbAMP DRAMP Antifungipept

Other

uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeru
Evidence 14 Activity

Activity

MIC
Antifungal
12 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

dbAMP DRAMP Antifungipept

Other

uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller
Evidence 15 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

Enterobacter cloacae ATCC 13047

Source & Reference

dbAMP DRAMP Antifungipept

Other

typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller-Hinton broth)(provided by Chunfeng Wa
Evidence 16 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Pseudomonas aeruginosa ATCC 7700

Source & Reference

dbAMP DRAMP Antifungipept

Other

ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller-Hinton broth)(provided by Chunfeng Wang).
Evidence 17 Activity

Activity

MIC
Antiparasitic
1 µM

Target

Escherichia coli ATCC 25922 or ML-35

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against E. coli ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM)
Evidence 18 Activity

Activity

MIC
Antiparasitic
1 µM

Target

S. enterica serovar Typhimurium ATCC 14028

Source & Reference

DRAMP

Other

active against E. coli ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S.
Evidence 19 Activity

Activity

MIC
Antiparasitic
1 µM

Target

S. marcescens ATCC8100

Source & Reference

DRAMP

Other

li ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or
Evidence 20 Activity

Activity

MIC
Antiparasitic
>128 µM

Target

S.aureus ATCC 25923

Source & Reference

DRAMP

Other

S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. p
Evidence 21 Activity

Activity

MIC
Antiparasitic
12-25 µg/mL

Target

S. enterica serovar typhimurium LT2 or ATCC 14028

Source & Reference

DRAMP

Other

uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeru
Evidence 22 Activity

Activity

MIC
Antiparasitic
12 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

DRAMP

Other

uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller
Evidence 23 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

Enterobacter cloacae ATCC 13047

Source & Reference

DRAMP

Other

typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller-Hinton broth)(provided by Chunfeng Wa
Evidence 24 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

Pseudomonas aeruginosa ATCC 7700

Source & Reference

DRAMP

Other

ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller-Hinton broth)(provided by Chunfeng Wang).
Evidence 25 Activity

Activity

MIC
Antiviral
1 µM

Target

Escherichia coli ATCC 25922 or ML-35

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
active against E. coli ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM)
Evidence 26 Activity

Activity

MIC
Antiviral
1 µM

Target

S. enterica serovar Typhimurium ATCC 14028

Source & Reference

DRAMP

Other

active against E. coli ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S.
Evidence 27 Activity

Activity

MIC
Antiviral
1 µM

Target

S. marcescens ATCC8100

Source & Reference

DRAMP

Other

li ATCC 25922 or ML-35 (MIC 1 uM), S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or
Evidence 28 Activity

Activity

MIC
Antiviral
>128 µM

Target

S.aureus ATCC 25923

Source & Reference

DRAMP

Other

S. enterica serovar Typhimurium ATCC 14028 (MIC 1 uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. p
Evidence 29 Activity

Activity

MIC
Antiviral
12-25 µg/mL

Target

S. enterica serovar typhimurium LT2 or ATCC 14028

Source & Reference

DRAMP

Other

uM), S. marcescens ATCC8100 (MIC 1 uM), S.aureus ATCC 25923 (MIC >128 uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeru
Evidence 30 Activity

Activity

MIC
Antiviral
12 µg/mL

Target

Klebsiella pneumoniae ATCC 13883

Source & Reference

DRAMP

Other

uM). Active against S. enterica serovar typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller
Evidence 31 Activity

Activity

MIC
Antiviral
25 µg/mL

Target

Enterobacter cloacae ATCC 13047

Source & Reference

DRAMP

Other

typhimurium LT2 or ATCC 14028 (MIC 12-25 ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller-Hinton broth)(provided by Chunfeng Wa
Evidence 32 Activity

Activity

MIC
Antiviral
50 µg/mL

Target

Pseudomonas aeruginosa ATCC 7700

Source & Reference

DRAMP

Other

ug/ml), K. pneumoniae ATCC 13883(MIC 12 ug/ml), E. cloacae ATCC 13047 (MIC 25 ug/ml) and P. aeruginosa ATCC 7700(MIC 50 ug/ml). (Mueller-Hinton broth)(provided by Chunfeng Wang).