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Peptide record

TPDB14932

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB14932
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 SATPdb iACP-DRLF pep-lab AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
RLFDKIRQVIRKF
Physicochemical Analysis
C80H135N25O17
ANCEGHMPSTWY
R
1719.11
12.13
5
1
6
+4
2.85
-0.438
112.31
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
3
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
2
I
1
L
2
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 1 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C80H135N25O17
1719.11
12.13
+4
2.85
-0.438
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
20 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against E. coli (MIC 20 uM).
Evidence 2 Activity

Activity

MIC
Antifungal
20 µM

Target

Escherichia coli

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against E. coli (MIC 20 uM).
Evidence 3 Activity

Activity

MIC
Antiparasitic
20 µM

Target

Escherichia coli

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
active against E. coli (MIC 20 uM).
Evidence 4 Activity

Activity

MIC
Antiviral
20 µM

Target

Escherichia coli

Source & Reference

dbAMP 3.0 DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
active against E. coli (MIC 20 uM).
Evidence 5 Activity

Activity

50% cell death
Toxicity
33.7 µM
Cytotoxic
50% cell death | 33.7 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Anti-human immunodeficiency virus type 1 activities of antimicrobial peptides derived from human and bovine cathelicidins | Antimicrob Agents Chemother | 2008