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Peptide record

TPDB14908

Antibacterial Antifungal standard
97 amino acids
Basic Information
3D PDB MODEL
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TPDB14908
Antibacterial Antifungal
Anti-infective peptides
dbAMP Peptipedia Antifungipept CAFPdb
standard
No
A 97-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
QYEALTAAILTKLSKMWHSDTLNFLGHTCHVSRTPTVKRFKLYWKGKFWCPGWAPFSGTSRTKSRSGSAREATKSFVDQALQRRLITQQEADLWLKG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C504H782N144O137S3
LT
11146.82
10.67
19
6
36
+10
1.89
-0.534
65.46
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
30605
2.75
29
Residue Composition
number
8
A
7
R
1
N
3
D
2
C
3
E
5
Q
6
G
3
H
2
I
10
L
9
K
1
M
5
F
3
P
9
S
10
T
5
W
2
Y
3
V
Amino Acid Distribution
A: 8 R: 7 N: 1 D: 3 C: 2 E: 3 Q: 5 G: 6 H: 3 I: 2 L: 10 K: 9 M: 1 F: 5 P: 3 S: 9 T: 10 W: 5 Y: 2 V: 3
Chemical Descriptors
97 reviewed residue count
C504H782N144O137S3 sequence-only estimate (linear, free termini)
11146.82 sequence-only estimate (linear, free termini)
10.67 sequence-only estimate (linear, free termini)
+10 sequence-only estimate (linear, free termini)
1.89 sequence-only estimate (linear, free termini)
-0.534 sequence-only estimate (linear, free termini)
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.51-1.02 µM

Target

V. alginolyticus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
The recombinant peptide (rPtALF7) is active against Gram- V. alginolyticus (MIC 0.51-1.02 uM), E. tarda (MIC 2.04-4.07 uM), P. aeruginosa (MIC 1.02-2.04 uM), Gram+ M. luteus (MIC 32.5
Evidence 2 Activity

Activity

MIC
Antibacterial
2.04-4.07 µM

Target

E. tarda

Source & Reference

dbAMP

Other

ecombinant peptide (rPtALF7) is active against Gram- V. alginolyticus (MIC 0.51-1.02 uM), E. tarda (MIC 2.04-4.07 uM), P. aeruginosa (MIC 1.02-2.04 uM), Gram+ M. luteus (MIC 32.59-65.19 uM), S. aureus (MIC 8
Evidence 3 Activity

Activity

MIC
Antibacterial
1.02-2.04 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

is active against Gram- V. alginolyticus (MIC 0.51-1.02 uM), E. tarda (MIC 2.04-4.07 uM), P. aeruginosa (MIC 1.02-2.04 uM), Gram+ M. luteus (MIC 32.59-65.19 uM), S. aureus (MIC 8.15-16.3 uM), and funus P.pastoris
Evidence 4 Activity

Activity

MIC
Antibacterial
32.59-65.19 µM

Target

M. luteus

Source & Reference

dbAMP

Other

(MIC 0.51-1.02 uM), E. tarda (MIC 2.04-4.07 uM), P. aeruginosa (MIC 1.02-2.04 uM), Gram+ M. luteus (MIC 32.59-65.19 uM), S. aureus (MIC 8.15-16.3 uM), and funus P.pastoris (MIC >130.37 uM).
Evidence 5 Activity

Activity

MIC
Antibacterial
8.15-16.3 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

IC 2.04-4.07 uM), P. aeruginosa (MIC 1.02-2.04 uM), Gram+ M. luteus (MIC 32.59-65.19 uM), S. aureus (MIC 8.15-16.3 uM), and funus P.pastoris (MIC >130.37 uM).
Evidence 6 Activity

Activity

MIC
Antibacterial
>130.37 µM

Target

P.pastoris

Source & Reference

dbAMP

Other

2-2.04 uM), Gram+ M. luteus (MIC 32.59-65.19 uM), S. aureus (MIC 8.15-16.3 uM), and funus P.pastoris (MIC >130.37 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
0.51-1.02 µM

Target

V. alginolyticus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
The recombinant peptide (rPtALF7) is active against Gram- V. alginolyticus (MIC 0.51-1.02 uM), E. tarda (MIC 2.04-4.07 uM), P. aeruginosa (MIC 1.02-2.04 uM), Gram+ M. luteus (MIC 32.5
Evidence 8 Activity

Activity

MIC
Antifungal
2.04-4.07 µM

Target

E. tarda

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ecombinant peptide (rPtALF7) is active against Gram- V. alginolyticus (MIC 0.51-1.02 uM), E. tarda (MIC 2.04-4.07 uM), P. aeruginosa (MIC 1.02-2.04 uM), Gram+ M. luteus (MIC 32.59-65.19 uM), S. aureus (MIC 8
Evidence 9 Activity

Activity

MIC
Antifungal
1.02-2.04 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP CAFPdb Antifungipept

Other

is active against Gram- V. alginolyticus (MIC 0.51-1.02 uM), E. tarda (MIC 2.04-4.07 uM), P. aeruginosa (MIC 1.02-2.04 uM), Gram+ M. luteus (MIC 32.59-65.19 uM), S. aureus (MIC 8.15-16.3 uM), and funus P.pastoris
Evidence 10 Activity

Activity

MIC
Antifungal
32.59-65.19 µM

Target

M. luteus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 0.51-1.02 uM), E. tarda (MIC 2.04-4.07 uM), P. aeruginosa (MIC 1.02-2.04 uM), Gram+ M. luteus (MIC 32.59-65.19 uM), S. aureus (MIC 8.15-16.3 uM), and funus P.pastoris (MIC >130.37 uM).
Evidence 11 Activity

Activity

MIC
Antifungal
8.15-16.3 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

IC 2.04-4.07 uM), P. aeruginosa (MIC 1.02-2.04 uM), Gram+ M. luteus (MIC 32.59-65.19 uM), S. aureus (MIC 8.15-16.3 uM), and funus P.pastoris (MIC >130.37 uM).
Evidence 12 Activity

Activity

MIC
Antifungal
>130.37 µM

Target

P.pastoris

Source & Reference

dbAMP CAFPdb Antifungipept

Other

2-2.04 uM), Gram+ M. luteus (MIC 32.59-65.19 uM), S. aureus (MIC 8.15-16.3 uM), and funus P.pastoris (MIC >130.37 uM).