TPDB

3D PDB MODEL

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TPDB ID TPDB14885

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 127-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.

Sequence

QVQLVESGGGSVQAGGSLRLSCSASGYTYISGWFRQAPGKGLEWVAAIRSSDGTTYYADSVKGRFTISQDNAKNTVYLQMNSLKPEDTAMYYCAATEVAGWPLDIGIYDYWGQGTQVTVSSHHHHHH

FASTA

>TPDB14885|Antibacterial|length=127
QVQLVESGGGSVQAGGSLRLSCSASGYTYISGWFRQAPGKGLEWVAAIRSSDGTTYYADSVKGRFTISQDNAKNTVYLQMNSLKPEDTAMYYCAATEVAGWPLDIGIYDYWGQGTQVTVSSHHHHHH

Formula C612H914N170O191S4

Absent Amino Acids

Common Amino Acids G

Mass 13837.25

PI 6.31

Basic Residues 14

Acidic Residues 10

Hydrophobic Residues 49

Net Charge -2

Boman Index 13.13

Hydrophobicity -0.384

Aliphatic Index 66.06

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 35535

Absorbance 280nm 256.81

Polar Residues 45

number

11

A

4

R

3

N

6

D

2

C

4

E

8

Q

15

G

6

H

5

I

7

L

4

K

2

M

2

F

3

P

14

S

9

T

4

W

9

Y

9

V

Amino Acid Distribution

A: 11 R: 4 N: 3 D: 6 C: 2 E: 4 Q: 8 G: 15 H: 6 I: 5 L: 7 K: 4 M: 2 F: 2 P: 3 S: 14 T: 9 W: 4 Y: 9 V: 9

Length

127

Formula

C612H914N170O191S4

Mass

13837.25

PI

6.31

Net Charge

-2

Boman Index

13.13

Hydrophobicity

-0.384

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.