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Peptide record

TPDB14876

Antibacterial Antifungal standard
75 amino acids
Basic Information
3D PDB MODEL
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TPDB14876
Antibacterial Antifungal
Anti-infective peptides
dbAMP Peptipedia Antifungipept
standard
No
A 75-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
QPDALNVPSTCCFTFSSKKISLQRLKSYVITTSRCPQKAVIFRTKLGKEICADPKEKWVQNYMKHLGRKAHTLKT
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C383H627N109O105S5
K
8599.16
10.39
17
4
25
+11
1.89
-0.501
72.80
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
8730
1.02
25
Residue Composition
number
4
A
4
R
2
N
2
D
4
C
2
E
4
Q
2
G
2
H
4
I
6
L
11
K
1
M
3
F
4
P
6
S
7
T
1
W
2
Y
4
V
Amino Acid Distribution
A: 4 R: 4 N: 2 D: 2 C: 4 E: 2 Q: 4 G: 2 H: 2 I: 4 L: 6 K: 11 M: 1 F: 3 P: 4 S: 6 T: 7 W: 1 Y: 2 V: 4
Chemical Descriptors
75 reviewed residue count
C383H627N109O105S5 sequence-only estimate (linear, free termini)
8599.16 sequence-only estimate (linear, free termini)
10.39 sequence-only estimate (linear, free termini)
+11 sequence-only estimate (linear, free termini)
1.89 sequence-only estimate (linear, free termini)
-0.501 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
At 10 ug/ml, it killed 76% E. coli.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
At 10 ug/ml, it killed 76% E. coli.