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Peptide record

TPDB14874

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
93 amino acids
Basic Information
3D PDB MODEL
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TPDB14874
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia Antifp Antifungipept CAFPdb
standard
No
A 93-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, Antifp, and other sources, with an available 3D structural model.
Sequence
QNICPRVNRIVTPCVAYGLGRAPIAPCCRALNDLRFVNTRNLRRAACRCLVGVVNRNPGLRRNPRFQNIPRDCRNTFVRPFWWRPRIQCGRIN
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C469H768N166O116S8
EHKMS
R
10844.78
12.17
19
2
33
+17
2.85
-0.405
81.72
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
12990
1.20
26
Residue Composition
number
6
A
19
R
11
N
2
D
8
C
0
E
3
Q
5
G
0
H
6
I
6
L
0
K
0
M
4
F
9
P
0
S
3
T
2
W
1
Y
8
V
Amino Acid Distribution
A: 6 R: 19 N: 11 D: 2 C: 8 E: 0 Q: 3 G: 5 H: 0 I: 6 L: 6 K: 0 M: 0 F: 4 P: 9 S: 0 T: 3 W: 2 Y: 1 V: 8
Chemical Descriptors
93 main sequence record
C469H768N166O116S8 sequence-only estimate (linear, free termini)
10844.78 sequence-only estimate (linear, free termini)
12.17 sequence-only estimate (linear, free termini)
+17 sequence-only estimate (linear, free termini)
2.85 sequence-only estimate (linear, free termini)
-0.405 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A potent antimicrobial protein from onion seeds showing sequence homology to plant lipid transfer proteins. | Plant Physiol | 1995
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Human fibroblasts

Target

Human fibroblasts

Source & Reference

NA
DBAASP
A potent antimicrobial protein from onion seeds showing sequence homology to plant lipid transfer proteins. | Plant Physiol | 1995