TPDB

3D PDB MODEL

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TPDB ID TPDB14870

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 255-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

QKLPVPIPPPTNPPVAAFHNSVATNSKGGQDVSVKLAATNLGNKHVQPIAEVFAKGNTQGGNVLRGATVGVQGHGLGASVTKTQDGIAESFRKQAEANLRLGDSASLIGKVSQTDTKIKGIDFKPQLSSSSLALQGDRLGASISRDVNRGVSDTLTKSISANVFRNDNHNLDASVFRSDVRQNNGFNFQKTGGMLDYSHANGHGLNAGLTRFSGIGNQANVGGYSTLFRSNDGLTSLKANAGGSQWLSGPFANQR

FASTA

>TPDB14870|Antibacterial|length=255
QKLPVPIPPPTNPPVAAFHNSVATNSKGGQDVSVKLAATNLGNKHVQPIAEVFAKGNTQGGNVLRGATVGVQGHGLGASVTKTQDGIAESFRKQAEANLRLGDSASLIGKVSQTDTKIKGIDFKPQLSSSSLALQGDRLGASISRDVNRGVSDTLTKSISANVFRNDNHNLDASVFRSDVRQNNGFNFQKTGGMLDYSHANGHGLNAGLTRFSGIGNQANVGGYSTLFRSNDGLTSLKANAGGSQWLSGPFANQR

Formula C1150H1844N356O369S1

Absent Amino Acids C

Common Amino Acids G

Mass 26593.51

PI 10.56

Basic Residues 32

Acidic Residues 16

Hydrophobic Residues 86

Net Charge +11

Boman Index 46.46

Hydrophobicity -0.433

Aliphatic Index 75.37

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 8480

Absorbance 280nm 31.89

Polar Residues 81

number

23

A

12

R

23

N

13

D

0

C

3

E

15

Q

32

G

6

H

9

I

21

L

14

K

1

M

11

F

10

P

26

S

15

T

1

W

2

Y

18

V

Amino Acid Distribution

A: 23 R: 12 N: 23 D: 13 C: 0 E: 3 Q: 15 G: 32 H: 6 I: 9 L: 21 K: 14 M: 1 F: 11 P: 10 S: 26 T: 15 W: 1 Y: 2 V: 18

Length

255

Formula

C1150H1844N356O369S1

Mass

26593.51

PI

10.56

Net Charge

+11

Boman Index

46.46

Hydrophobicity

-0.433

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.