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Peptide record

TPDB14852

Antibacterial Antifungal standard
127 amino acids
Basic Information
3D PDB MODEL
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TPDB14852
Antibacterial Antifungal
Anti-infective peptides
dbAMP Peptipedia Antifungipept
standard
No
A 127-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
QGVFEDCCLAYHYPIGWAVLRRAWTYRIQEVSGSCNLPAAIFYLPKRHRKVCGNPKSREVQRAMKLLDARNKVFAKLHHNTQTFQAGPHAVKKLSSGNSKLSSSKFSNPISSSKRNVSLLISANSGL
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C629H1004N190O174S5
S
14172.36
10.69
25
5
48
+15
1.82
-0.388
79.13
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
17210
1.21
40
Residue Composition
number
11
A
9
R
8
N
2
D
4
C
3
E
5
Q
7
G
5
H
5
I
12
L
11
K
1
M
5
F
6
P
16
S
3
T
2
W
4
Y
8
V
Amino Acid Distribution
A: 11 R: 9 N: 8 D: 2 C: 4 E: 3 Q: 5 G: 7 H: 5 I: 5 L: 12 K: 11 M: 1 F: 5 P: 6 S: 16 T: 3 W: 2 Y: 4 V: 8
Chemical Descriptors
127 reviewed residue count
C629H1004N190O174S5 sequence-only estimate (linear, free termini)
14172.36 sequence-only estimate (linear, free termini)
10.69 sequence-only estimate (linear, free termini)
+15 sequence-only estimate (linear, free termini)
1.82 sequence-only estimate (linear, free termini)
-0.388 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
At 10 ug/ml, it killed 68% E. coli and 48% S. aureus. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
At 10 ug/ml, it killed 68% E. coli and 48% S. aureus. Updated 7/2021