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Peptide record

TPDB14831

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
94 amino acids
Basic Information
3D PDB MODEL
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TPDB14831
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
dbAMP Peptipedia Antifungipept
standard
No
A 94-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
PITYLDAILAAVRLLNQRISGPCILRLREAQPRPGWVGTLQRRREVSFLVEDGPCPPGVDCRSCEPGALQHCVGTVSIEQQPTAELRCRPLRPQ
Physicochemical Analysis
C452H745N141O130S6
KM
R
10427.11
8.31
13
9
32
+3
23.47
-0.245
94.36
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
7365
70.63
23
Residue Composition
number
6
A
12
R
1
N
3
D
6
C
6
E
7
Q
7
G
1
H
5
I
11
L
0
K
0
M
1
F
11
P
4
S
4
T
1
W
1
Y
7
V
Amino Acid Distribution
A: 6 R: 12 N: 1 D: 3 C: 6 E: 6 Q: 7 G: 7 H: 1 I: 5 L: 11 K: 0 M: 0 F: 1 P: 11 S: 4 T: 4 W: 1 Y: 1 V: 7
Chemical Descriptors
94
C452H745N141O130S6
10427.11
8.31
+3
23.47
-0.245
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.25 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli (MIC 2..5 uM), S. aureus (MIC 1.25 uM), and P. aeruginosa (MIC 0.63 uM) (see the ref). CATH-B1) could inhibit Pseudorabies virus
Evidence 2 Activity

Activity

MIC
Antibacterial
0.63 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP

Other

Active against E. coli (MIC 2..5 uM), S. aureus (MIC 1.25 uM), and P. aeruginosa (MIC 0.63 uM) (see the ref). CATH-B1) could inhibit Pseudorabies virus (PRV) ( Ye et al., 2023 ).
Evidence 3 Activity

Activity

MIC
Antifungal
1.25 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli (MIC 2..5 uM), S. aureus (MIC 1.25 uM), and P. aeruginosa (MIC 0.63 uM) (see the ref). CATH-B1) could inhibit Pseudorabies virus
Evidence 4 Activity

Activity

MIC
Antifungal
0.63 µM

Target

Pseudomonas aeruginosa

Source & Reference

dbAMP Antifungipept

Other

Active against E. coli (MIC 2..5 uM), S. aureus (MIC 1.25 uM), and P. aeruginosa (MIC 0.63 uM) (see the ref). CATH-B1) could inhibit Pseudorabies virus (PRV) ( Ye et al., 2023 ).
Evidence 5 Activity

Activity

MIC
Antiparasitic
1.25 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against E. coli (MIC 2..5 uM), S. aureus (MIC 1.25 uM), and P. aeruginosa (MIC 0.63 uM) (see the ref). CATH-B1) could inhibit Pseudorabies virus
Evidence 6 Activity

Activity

MIC
Antiparasitic
0.63 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

Active against E. coli (MIC 2..5 uM), S. aureus (MIC 1.25 uM), and P. aeruginosa (MIC 0.63 uM) (see the ref). CATH-B1) could inhibit Pseudorabies virus (PRV) ( Ye et al., 2023 ).
Evidence 7 Activity

Activity

MIC
Antiviral
1.25 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against E. coli (MIC 2..5 uM), S. aureus (MIC 1.25 uM), and P. aeruginosa (MIC 0.63 uM) (see the ref). CATH-B1) could inhibit Pseudorabies virus
Evidence 8 Activity

Activity

MIC
Antiviral
0.63 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

Active against E. coli (MIC 2..5 uM), S. aureus (MIC 1.25 uM), and P. aeruginosa (MIC 0.63 uM) (see the ref). CATH-B1) could inhibit Pseudorabies virus (PRV) ( Ye et al., 2023 ).