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Peptide record

TPDB14830

Antibacterial Antifungal standard
92 amino acids
Basic Information
3D PDB MODEL
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TPDB14830
Antibacterial Antifungal
Anti-infective peptides
dbAMP Peptipedia Antifungipept
standard
No
A 92-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
PGGPGSAPPATCRYWCRTPQGQAYCCEGVDEPEGPVGVKIGSCPRVRPQCPPVRTFGPPSPCSNDFKCFGSDKCCYDICLEQHVCKPLSFFG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C429H647N119O126S12
M
P
9872.30
7.31
10
8
22
+1
1.40
-0.388
39.13
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
10720
1.09
29
Residue Composition
number
3
A
5
R
1
N
4
D
12
C
4
E
4
Q
11
G
1
H
2
I
2
L
4
K
0
M
5
F
15
P
6
S
3
T
1
W
3
Y
6
V
Amino Acid Distribution
A: 3 R: 5 N: 1 D: 4 C: 12 E: 4 Q: 4 G: 11 H: 1 I: 2 L: 2 K: 4 M: 0 F: 5 P: 15 S: 6 T: 3 W: 1 Y: 3 V: 6
Chemical Descriptors
92 reviewed residue count
C429H647N119O126S12 sequence-only estimate (linear, free termini)
9872.30 sequence-only estimate (linear, free termini)
7.31 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
1.40 sequence-only estimate (linear, free termini)
-0.388 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Able to agglutinate G+ and G- bacteria and inhibit bacterial growth (bacteria-agglutinating). MrCrs peptide sequence contains a long WAP (whey acidic protein) domain, ~50% Similar to AP1555 . In addition, MrCrs peptide sequence contains six N-myristoylation sites and two protein kinase C phosphorylation sites (read the article).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Able to agglutinate G+ and G- bacteria and inhibit bacterial growth (bacteria-agglutinating). MrCrs peptide sequence contains a long WAP (whey acidic protein) domain, ~50% Similar to AP1555 . In addition, MrCrs peptide sequence contains six N-myristoylation sites and two protein kinase C phosphorylation sites (read the article).