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Peptide record

TPDB14813

Antibacterial Antifungal Toxicity standard
63 amino acids
Basic Information
3D PDB MODEL
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TPDB14813
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 63-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
NVTPATKPTPSKPGYCRVMDELILCPDPPLSKDLCKNDSDCPGAQKCCYRTCIMQCLPPIFRE
Physicochemical Analysis
C300H485N81O91S10
HW
P
7003.24
7.48
8
7
17
+1
15.72
-0.397
61.90
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
3480
49.69
21
Residue Composition
number
2
A
3
R
2
N
5
D
8
C
2
E
2
Q
2
G
0
H
3
I
5
L
5
K
2
M
1
F
10
P
3
S
4
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 2 R: 3 N: 2 D: 5 C: 8 E: 2 Q: 2 G: 2 H: 0 I: 3 L: 5 K: 5 M: 2 F: 1 P: 10 S: 3 T: 4 W: 0 Y: 2 V: 2
Chemical Descriptors
63
C300H485N81O91S10
7003.24
7.48
+1
15.72
-0.397
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.5 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
recombinant peptide is active against S. aureus ATCC 25923 (MIC 1.5 ug/ml), E.coli ATCC 25922 (MIC >250 ug/ml), B. subtilis ATCC 6633 (MIC 5.9 ug/ml), and C. albica
Evidence 2 Activity

Activity

MIC
Antibacterial
>250 µg/mL

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

recombinant peptide is active against S. aureus ATCC 25923 (MIC 1.5 ug/ml), E.coli ATCC 25922 (MIC >250 ug/ml), B. subtilis ATCC 6633 (MIC 5.9 ug/ml), and C. albicans ATCC 20032 (MIC 5.9 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
5.9 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP

Other

active against S. aureus ATCC 25923 (MIC 1.5 ug/ml), E.coli ATCC 25922 (MIC >250 ug/ml), B. subtilis ATCC 6633 (MIC 5.9 ug/ml), and C. albicans ATCC 20032 (MIC 5.9 ug/ml).
Evidence 4 Activity

Activity

MIC
Antibacterial
5.9 µg/mL

Target

Candida albicans ATCC 20032

Source & Reference

dbAMP

Other

.5 ug/ml), E.coli ATCC 25922 (MIC >250 ug/ml), B. subtilis ATCC 6633 (MIC 5.9 ug/ml), and C. albicans ATCC 20032 (MIC 5.9 ug/ml).
Evidence 5 Activity

Activity

MIC
Antifungal
1.5 µg/mL

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
recombinant peptide is active against S. aureus ATCC 25923 (MIC 1.5 ug/ml), E.coli ATCC 25922 (MIC >250 ug/ml), B. subtilis ATCC 6633 (MIC 5.9 ug/ml), and C. albica
Evidence 6 Activity

Activity

MIC
Antifungal
>250 µg/mL

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

recombinant peptide is active against S. aureus ATCC 25923 (MIC 1.5 ug/ml), E.coli ATCC 25922 (MIC >250 ug/ml), B. subtilis ATCC 6633 (MIC 5.9 ug/ml), and C. albicans ATCC 20032 (MIC 5.9 ug/ml).
Evidence 7 Activity

Activity

MIC
Antifungal
5.9 µg/mL

Target

B. subtilis ATCC 6633

Source & Reference

dbAMP CAFPdb Antifungipept

Other

active against S. aureus ATCC 25923 (MIC 1.5 ug/ml), E.coli ATCC 25922 (MIC >250 ug/ml), B. subtilis ATCC 6633 (MIC 5.9 ug/ml), and C. albicans ATCC 20032 (MIC 5.9 ug/ml).
Evidence 8 Activity

Activity

MIC
Antifungal
5.9 µg/mL

Target

Candida albicans ATCC 20032

Source & Reference

dbAMP CAFPdb Antifungipept

Other

.5 ug/ml), E.coli ATCC 25922 (MIC >250 ug/ml), B. subtilis ATCC 6633 (MIC 5.9 ug/ml), and C. albicans ATCC 20032 (MIC 5.9 ug/ml).
Evidence 9 Activity

Activity

1% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 100 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Snake venom-like waprin from the frog of Ceratophrys calcarata contains antimicrobial function. | Gene | 2013
Evidence 10 Activity

Activity

2% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 200 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Snake venom-like waprin from the frog of Ceratophrys calcarata contains antimicrobial function. | Gene | 2013
Evidence 11 Activity

Activity

3% Hemolysis
Toxicity
400 µg/mL
Hemolytic Cytotoxic
3% Hemolysis | 400 | µg/mL | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Snake venom-like waprin from the frog of Ceratophrys calcarata contains antimicrobial function. | Gene | 2013
Evidence 12 Activity

Activity

1% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Snake venom-like waprin from the frog of Ceratophrys calcarata contains antimicrobial function. | Gene | 2013
Evidence 13 Activity

Activity

2% Hemolysis
Toxicity
400 µg/mL
Hemolytic Cytotoxic
2% Hemolysis | 400 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Snake venom-like waprin from the frog of Ceratophrys calcarata contains antimicrobial function. | Gene | 2013