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Peptide record

TPDB14805

Antibacterial Anticancer Antifungal Antiparasitic standard
79 amino acids
Basic Information
3D PDB MODEL
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TPDB14805
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 79-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
NPLIPAIYIGATVGPSVWAYLVALVGAAAVTAANIRRASSDNHSCAGNRGWCRSKCFRHEYVDTYYSAVCGRYFCCRSR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C380H582N114O106S6
QM
A
8635.86
9.11
11
3
36
+6
1.38
0.072
75.44
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
20315
2.35
26
Residue Composition
number
12
A
8
R
4
N
2
D
6
C
1
E
0
Q
6
G
2
H
4
I
3
L
1
K
0
M
2
F
3
P
7
S
3
T
2
W
6
Y
7
V
Amino Acid Distribution
A: 12 R: 8 N: 4 D: 2 C: 6 E: 1 Q: 0 G: 6 H: 2 I: 4 L: 3 K: 1 M: 0 F: 2 P: 3 S: 7 T: 3 W: 2 Y: 6 V: 7
Chemical Descriptors
79 main sequence record
C380H582N114O106S6 sequence-only estimate (linear, free termini)
8635.86 sequence-only estimate (linear, free termini)
9.11 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
1.38 sequence-only estimate (linear, free termini)
0.072 sequence-only estimate (linear, free termini)
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against Gram+ and Gram- bacteria as well as fungi such as C. albicans.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against Gram+ and Gram- bacteria as well as fungi such as C. albicans.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

active against Gram+ and Gram- bacteria as well as fungi such as C. albicans.