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Peptide record

TPDB14782

Antibacterial Anticancer Antifungal Antiparasitic standard
51 amino acids
Basic Information
3D PDB MODEL
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TPDB14782
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 51-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
MSWLNFLKYIAKYGKKAVSAAWKYKGKVLEWLNVGPTLEWVWQKLKKIAGL
Physicochemical Analysis
C291H447N69O65S1
RDCH
K
5984.23
10.49
10
2
28
+8
-2.29
-0.084
101.37
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
31970
534.24
9
Residue Composition
number
5
A
0
R
2
N
0
D
0
C
2
E
1
Q
4
G
0
H
2
I
7
L
10
K
1
M
1
F
1
P
2
S
1
T
5
W
3
Y
4
V
Amino Acid Distribution
A: 5 R: 0 N: 2 D: 0 C: 0 E: 2 Q: 1 G: 4 H: 0 I: 2 L: 7 K: 10 M: 1 F: 1 P: 1 S: 2 T: 1 W: 5 Y: 3 V: 4
Chemical Descriptors
51
C291H447N69O65S1
5984.23
10.49
+8
-2.29
-0.084
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
This plasmid-encoded peptide is active against food-related L. monocytogenes, S. simulans 22, S. aureus (MRSA), and S. agalactiae, thereby with a potential medical and food preservative use. Peptide stability : It is stable at an extremen acidic environment at high temperature. After 18 hours incubation with trypsin at 37 oC, ~90–95% of aureocin A53 remained intact (protease-insensitive:trypsin).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
This plasmid-encoded peptide is active against food-related L. monocytogenes, S. simulans 22, S. aureus (MRSA), and S. agalactiae, thereby with a potential medical and food preservative use. Peptide stability : It is stable at an extremen acidic environment at high temperature. After 18 hours incubation with trypsin at 37 oC, ~90–95% of aureocin A53 remained intact (protease-insensitive:trypsin).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

This plasmid-encoded peptide is active against food-related L. monocytogenes, S. simulans 22, S. aureus (MRSA), and S. agalactiae, thereby with a potential medical and food preservative use. Peptide stability : It is stable at an extremen acidic environment at high temperature. After 18 hours incubation with trypsin at 37 oC, ~90–95% of aureocin A53 remained intact (protease-insensitive:trypsin).