TPDB

3D PDB MODEL

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TPDB ID TPDB14775

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 255-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

MSGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGPFKFGLWGVALYGVLPSQIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPAVQTLSPGVTNNTDKD

FASTA

>TPDB14775|Antibacterial|length=255
MSGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGPFKFGLWGVALYGVLPSQIAKDDPNMMSKIVTSLPADDITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAKPTERPGVFTASIPGAPVLNISVNNSTPAVQTLSPGVTNNTDKD

Formula C1066H1688N308O358S5

Absent Amino Acids C

Common Amino Acids G

Mass 24707.28

PI 4.82

Basic Residues 16

Acidic Residues 18

Hydrophobic Residues 89

Net Charge -6

Boman Index 35.77

Hydrophobicity -0.049

Aliphatic Index 76.08

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 23490

Absorbance 280nm 95.07

Polar Residues 66

number

24

A

4

R

18

N

14

D

0

C

4

E

3

Q

48

G

4

H

11

I

14

L

8

K

5

M

5

F

19

P

30

S

14

T

4

W

1

Y

25

V

Amino Acid Distribution

A: 24 R: 4 N: 18 D: 14 C: 0 E: 4 Q: 3 G: 48 H: 4 I: 11 L: 14 K: 8 M: 5 F: 5 P: 19 S: 30 T: 14 W: 4 Y: 1 V: 25

Length

255

Formula

C1066H1688N308O358S5

Mass

24707.28

PI

4.82

Net Charge

-6

Boman Index

35.77

Hydrophobicity

-0.049

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.