TPDB

3D PDB MODEL

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TPDB ID TPDB14746

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 198-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

MPLGLLWLGLALLGALHAQAQDSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKAVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG

FASTA

>TPDB14746|Antibacterial|length=198
MPLGLLWLGLALLGALHAQAQDSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYWIRTFVPGSQPGEFTLGNIKSYPGLTSYLVRVVSTNYNQHAMVFFKAVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG

Formula C1032H1595N265O290S5

Absent Amino Acids

Common Amino Acids L

Mass 22514.92

PI 9.22

Basic Residues 25

Acidic Residues 18

Hydrophobic Residues 83

Net Charge +4

Boman Index 27.11

Hydrophobicity -0.256

Aliphatic Index 89.09

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 31525

Absorbance 280nm 140.02

Polar Residues 57

number

10

A

7

R

10

N

9

D

2

C

9

E

12

Q

13

G

3

H

10

I

23

L

15

K

3

M

11

F

12

P

13

S

10

T

3

W

10

Y

13

V

Amino Acid Distribution

A: 10 R: 7 N: 10 D: 9 C: 2 E: 9 Q: 12 G: 13 H: 3 I: 10 L: 23 K: 15 M: 3 F: 11 P: 12 S: 13 T: 10 W: 3 Y: 10 V: 13

Length

198

Formula

C1032H1595N265O290S5

Mass

22514.92

PI

9.22

Net Charge

+4

Boman Index

27.11

Hydrophobicity

-0.256

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.