TPDB

3D PDB MODEL

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TPDB ID TPDB14744

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 198-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

MPLGLLWLGLALLGALHAQAQDSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYAIATFVPGSQPGEFTLGNIKSYPGLTSFLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG

FASTA

>TPDB14744|Antibacterial|length=198
MPLGLLWLGLALLGALHAQAQDSTSDLIPAPPLSKVPLQQNFQDNQFQGKWYVVGLAGNAILREDKDPQKMYATIYELKEDKSYNVTSVLFRKKKCDYAIATFVPGSQPGEFTLGNIKSYPGLTSFLVRVVSTNYNQHAMVFFKKVSQNREYFKITLYGRTKELTSELKENFIRFSKSLGLPENHIVFPVPIDQCIDG

Formula C1024H1590N262O289S5

Absent Amino Acids

Common Amino Acids L

Mass 22355.77

PI 9.23

Basic Residues 25

Acidic Residues 18

Hydrophobic Residues 83

Net Charge +4

Boman Index 28.78

Hydrophobicity -0.218

Aliphatic Index 89.60

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 24535

Absorbance 280nm 109.75

Polar Residues 56

number

11

A

6

R

10

N

9

D

2

C

9

E

12

Q

13

G

3

H

10

I

23

L

16

K

3

M

12

F

12

P

13

S

10

T

2

W

9

Y

13

V

Amino Acid Distribution

A: 11 R: 6 N: 10 D: 9 C: 2 E: 9 Q: 12 G: 13 H: 3 I: 10 L: 23 K: 16 M: 3 F: 12 P: 12 S: 13 T: 10 W: 2 Y: 9 V: 13

Length

198

Formula

C1024H1590N262O289S5

Mass

22355.77

PI

9.23

Net Charge

+4

Boman Index

28.78

Hydrophobicity

-0.218

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.