TPDB

3D PDB MODEL

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TPDB ID TPDB14730

Activity

Antibacterial Anticancer Antifungal

Activity_category_statistics

Anti-infective peptides Cancer-related peptides

Database_Source

dbAMP DRAMP Peptipedia dbACP AFP-GFuse Antifungipept CAFPdb

Sequence_Type

standard

Has_Modification No

Description A 93-aa standard natural multi-activity (Antibacterial, Anticancer, and Antifungal) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.

Sequence

MLTELEKALNSIIDVYHKYSLIKGNFHAVYRDDLKKLLETECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEESHKE

FASTA

>TPDB14730|Antibacterial;Anticancer;Antifungal|length=93
MLTELEKALNSIIDVYHKYSLIKGNFHAVYRDDLKKLLETECPQYIRKKGADVWFKELDINTDGAVNFQEFLILVIKMGVAAHKKSHEESHKE

Formula C492H774N128O141S3

Absent Amino Acids

Common Amino Acids K

Mass 10834.51

PI 6.62

Basic Residues 19

Acidic Residues 15

Hydrophobic Residues 40

Net Charge -1

Boman Index 28.93

Hydrophobicity -0.397

Aliphatic Index 96.45

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 11460

Absorbance 280nm 105.77

Polar Residues 18

number

6

A

2

R

4

N

6

D

1

C

9

E

2

Q

4

G

5

H

7

I

10

L

12

K

2

M

4

F

1

P

4

S

3

T

1

W

4

Y

6

V

Amino Acid Distribution

A: 6 R: 2 N: 4 D: 6 C: 1 E: 9 Q: 2 G: 4 H: 5 I: 7 L: 10 K: 12 M: 2 F: 4 P: 1 S: 4 T: 3 W: 1 Y: 4 V: 6

Length

93

Formula

C492H774N128O141S3

Mass

10834.51

PI

6.62

Net Charge

-1

Boman Index

28.93

Hydrophobicity

-0.397

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP dbACP CAFPdb Antifungipept