TPDB

3D PDB MODEL

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TPDB ID TPDB14682

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 279-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

METLTVHAPSPSTNLPSYGNGAFSLSAPHVPGAGPLLVQVVYSFFQSPNMCLQALTQLEDYIKKHGASNPLTLQIISTNIGYFCNADRNLVLHPGISVYDAYHFAKPAPSQYDYRSMNMKQMSGNVTTPIVALAHYLWGNGAERSVNIANIGLKISPMKINQIKDIIKSGVVGTFPVSTKFTHATGDYNVITGAYLGNITLKTEGTLTISANGSWTYNGVVRSYDDKYDFNASTHRGIIGESLTRLGAMFSGKEYQILLPGEIHIKESGKRAAHHHHHH

FASTA

>TPDB14682|Antibacterial|length=279
METLTVHAPSPSTNLPSYGNGAFSLSAPHVPGAGPLLVQVVYSFFQSPNMCLQALTQLEDYIKKHGASNPLTLQIISTNIGYFCNADRNLVLHPGISVYDAYHFAKPAPSQYDYRSMNMKQMSGNVTTPIVALAHYLWGNGAERSVNIANIGLKISPMKINQIKDIIKSGVVGTFPVSTKFTHATGDYNVITGAYLGNITLKTEGTLTISANGSWTYNGVVRSYDDKYDFNASTHRGIIGESLTRLGAMFSGKEYQILLPGEIHIKESGKRAAHHHHHH

Formula C1366H2111N373O400S9

Absent Amino Acids

Common Amino Acids G

Mass 30447.59

PI 9.12

Basic Residues 36

Acidic Residues 17

Hydrophobic Residues 113

Net Charge +5

Boman Index 35.52

Hydrophobicity -0.179

Aliphatic Index 84.27

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 33475

Absorbance 280nm 109.94

Polar Residues 88

number

21

A

7

R

18

N

9

D

2

C

8

E

9

Q

25

G

15

H

21

I

22

L

14

K

7

M

9

F

15

P

24

S

20

T

2

W

15

Y

16

V

Amino Acid Distribution

A: 21 R: 7 N: 18 D: 9 C: 2 E: 8 Q: 9 G: 25 H: 15 I: 21 L: 22 K: 14 M: 7 F: 9 P: 15 S: 24 T: 20 W: 2 Y: 15 V: 16

Length

279

Formula

C1366H2111N373O400S9

Mass

30447.59

PI

9.12

Net Charge

+5

Boman Index

35.52

Hydrophobicity

-0.179

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.