TPDB

3D PDB MODEL

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TPDB ID TPDB14678

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 94-aa standard natural antibacterial peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.

Sequence

MELKHSISDYTEAEFLEFVKKICRAEGATEEDDNKLVREFERLTEHPDGSDLIYYPRDDREDSPEGIVKEIKEWRAANGKSGFKQGLEHHHHHH

FASTA

>TPDB14678|Antibacterial|length=94
MELKHSISDYTEAEFLEFVKKICRAEGATEEDDNKLVREFERLTEHPDGSDLIYYPRDDREDSPEGIVKEIKEWRAANGKSGFKQGLEHHHHHH

Formula C484H736N140O155S2

Absent Amino Acids

Common Amino Acids E

Mass 11060.13

PI 5.16

Basic Residues 22

Acidic Residues 23

Hydrophobic Residues 28

Net Charge -8

Boman Index 49.29

Hydrophobicity -1.174

Aliphatic Index 60.21

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 9970

Absorbance 280nm 90.14

Polar Residues 15

number

5

A

6

R

2

N

8

D

1

C

15

E

1

Q

6

G

8

H

5

I

6

L

8

K

1

M

4

F

3

P

5

S

3

T

1

W

3

Y

3

V

Amino Acid Distribution

A: 5 R: 6 N: 2 D: 8 C: 1 E: 15 Q: 1 G: 6 H: 8 I: 5 L: 6 K: 8 M: 1 F: 4 P: 3 S: 5 T: 3 W: 1 Y: 3 V: 3

Length

94

Formula

C484H736N140O155S2

Mass

11060.13

PI

5.16

Net Charge

-8

Boman Index

49.29

Hydrophobicity

-1.174

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.