TPDB

3D PDB MODEL

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TPDB ID TPDB14671

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 255-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEERKIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLRGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVV

FASTA

>TPDB14671|Antibacterial|length=255
MEFLKRSFAPLTEKQWQEIDNRAREIFKTQLYGRKFVDVEGPYGWEYAAHPLGEVEVLSDENEVVKWGLRKSLPLIELRATFTLDLWELDNLERGKPNVDLSSLEETVRKVAEFEDEVIFRGCEKSGVKGLLSFEERKIECGSTPKDLLEAIVRALSIFSKDGIEGPYTLVINTDRWINFLKEEAGHYPLEKRVEECLRGGKIITTPRIEDALVVSERGGDFKLILGQDLSIGYEDREKDAVRLFITETFTFQVV

Formula C1325H2083N347O396S4

Absent Amino Acids

Common Amino Acids E

Mass 29338.44

PI 4.68

Basic Residues 38

Acidic Residues 49

Hydrophobic Residues 101

Net Charge -13

Boman Index 81.09

Hydrophobicity -0.354

Aliphatic Index 94.75

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 36565

Absorbance 280nm 124.63

Polar Residues 45

number

11

A

18

R

6

N

15

D

3

C

34

E

5

Q

19

G

2

H

16

I

29

L

18

K

1

M

14

F

9

P

12

S

13

T

5

W

6

Y

19

V

Amino Acid Distribution

A: 11 R: 18 N: 6 D: 15 C: 3 E: 34 Q: 5 G: 19 H: 2 I: 16 L: 29 K: 18 M: 1 F: 14 P: 9 S: 12 T: 13 W: 5 Y: 6 V: 19

Length

255

Formula

C1325H2083N347O396S4

Mass

29338.44

PI

4.68

Net Charge

-13

Boman Index

81.09

Hydrophobicity

-0.354

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.