TPDB

3D PDB MODEL

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TPDB ID TPDB14668

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 256-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

MASSLAPRQVIRDGQFITSPNGKYKLVMQADGNLVLYEDGTKPIWNTTPVGPGAKAVMEFNLNLYNKAGQVAWSSNVYTAYLFEEFKDEAYLNLQDDGDFGIFSDEAKWGSIVLSRPEVGVKNKIIPTGTVMVPGTEYINGNYRLAFQGDGNLVIYQINPQVVIWATYTMGADRAVVQEDGNFVIYKGTTALWHTHTATGMPAYLKFTNTGKLFLSQPTLLWTLKRGSLSKPPKVIPGQHGPLDTTPIWSWPHDYP

FASTA

>TPDB14668|Antibacterial|length=256
MASSLAPRQVIRDGQFITSPNGKYKLVMQADGNLVLYEDGTKPIWNTTPVGPGAKAVMEFNLNLYNKAGQVAWSSNVYTAYLFEEFKDEAYLNLQDDGDFGIFSDEAKWGSIVLSRPEVGVKNKIIPTGTVMVPGTEYINGNYRLAFQGDGNLVIYQINPQVVIWATYTMGADRAVVQEDGNFVIYKGTTALWHTHTATGMPAYLKFTNTGKLFLSQPTLLWTLKRGSLSKPPKVIPGQHGPLDTTPIWSWPHDYP

Formula C1301H1975N331O373S6

Absent Amino Acids C

Common Amino Acids G

Mass 28413.35

PI 6.52

Basic Residues 25

Acidic Residues 22

Hydrophobic Residues 108

Net Charge -1

Boman Index 25.88

Hydrophobicity -0.236

Aliphatic Index 81.48

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 63370

Absorbance 280nm 223.03

Polar Residues 72

number

17

A

6

R

15

N

13

D

0

C

9

E

11

Q

24

G

4

H

14

I

21

L

15

K

6

M

10

F

18

P

12

S

21

T

8

W

13

Y

19

V

Amino Acid Distribution

A: 17 R: 6 N: 15 D: 13 C: 0 E: 9 Q: 11 G: 24 H: 4 I: 14 L: 21 K: 15 M: 6 F: 10 P: 18 S: 12 T: 21 W: 8 Y: 13 V: 19

Length

256

Formula

C1301H1975N331O373S6

Mass

28413.35

PI

6.52

Net Charge

-1

Boman Index

25.88

Hydrophobicity

-0.236

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.