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Peptide record

TPDB14661

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
70 amino acids
Basic Information
3D PDB MODEL
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TPDB14661
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia Antifungipept i2APP
standard
No
A 70-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
MAKEFGIPAAVAGTVINVVEAGGWVTTIVSILTAVGSGGLSLLAAAGRESIKAYLKKEIKKKGKRAVIAW
Physicochemical Analysis
C328H549N87O89S1
DCQH
A
7167.56
10.57
10
4
37
+6
7.21
0.549
117.14
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12490
174.26
10
Residue Composition
number
12
A
2
R
1
N
0
D
0
C
4
E
0
Q
9
G
0
H
7
I
5
L
8
K
1
M
1
F
1
P
4
S
4
T
2
W
1
Y
8
V
Amino Acid Distribution
A: 12 R: 2 N: 1 D: 0 C: 0 E: 4 Q: 0 G: 9 H: 0 I: 7 L: 5 K: 8 M: 1 F: 1 P: 1 S: 4 T: 4 W: 2 Y: 1 V: 8
Chemical Descriptors
70
C328H549N87O89S1
7167.56
10.57
+6
7.21
0.549
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-positive Bacillus, Staphylococcus (S. aureus, MRSA), and Listeria and Gram-negative Salmonella, E. coli, etc. Also anti-parasitic against T. brucei with an EC50 = 1-3 nM by targeting intracellular compartments ( Martínez-García M1, et al. 2018 ).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-positive Bacillus, Staphylococcus (S. aureus, MRSA), and Listeria and Gram-negative Salmonella, E. coli, etc. Also anti-parasitic against T. brucei with an EC50 = 1-3 nM by targeting intracellular compartments ( Martínez-García M1, et al. 2018 ).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against Gram-positive Bacillus, Staphylococcus (S. aureus, MRSA), and Listeria and Gram-negative Salmonella, E. coli, etc. Also anti-parasitic against T. brucei with an EC50 = 1-3 nM by targeting intracellular compartments ( Martínez-García M1, et al. 2018 ).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

Active against Gram-positive Bacillus, Staphylococcus (S. aureus, MRSA), and Listeria and Gram-negative Salmonella, E. coli, etc. Also anti-parasitic against T. brucei with an EC50 = 1-3 nM by targeting intracellular compartments ( Martínez-García M1, et al. 2018 ).