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Peptide record

TPDB14657

Antibacterial Anticancer Antifungal Antiparasitic standard
51 amino acids
Basic Information
3D PDB MODEL
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TPDB14657
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia AFP-GFuse Antifp Antifungipept
standard
No
A 51-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
MAAFMKLIQFLATKGQKYVSLAWKHKGTILKWINAGQSFEWIYKQIKKLWA
Physicochemical Analysis
C291H447N71O65S2
RDCP
K
6044.31
10.69
10
1
28
+8
-3.23
-0.020
93.92
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
24980
413.28
11
Residue Composition
number
6
A
0
R
1
N
0
D
0
C
1
E
4
Q
3
G
1
H
5
I
5
L
9
K
2
M
3
F
0
P
2
S
2
T
4
W
2
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 4 G: 3 H: 1 I: 5 L: 5 K: 9 M: 2 F: 3 P: 0 S: 2 T: 2 W: 4 Y: 2 V: 1
Chemical Descriptors
51
C291H447N71O65S2
6044.31
10.69
+8
-3.23
-0.020
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. saprophyticus (MIC 82.3-160 nM), S. hominis (MIC 160 nM), S. warneri (MIC 160 nM), E. faecalis (MIC 160 nM), including multidrug-resistant S. epidermidis strains causing biofilm-related infections (MIC 10-658 nM), S. aureus 1195 MRSA (MIC 160-329 nM), and vancomycin-resistant enterococci anti-VRE (MIC 82.3-329 nM).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. saprophyticus (MIC 82.3-160 nM), S. hominis (MIC 160 nM), S. warneri (MIC 160 nM), E. faecalis (MIC 160 nM), including multidrug-resistant S. epidermidis strains causing biofilm-related infections (MIC 10-658 nM), S. aureus 1195 MRSA (MIC 160-329 nM), and vancomycin-resistant enterococci anti-VRE (MIC 82.3-329 nM).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against S. saprophyticus (MIC 82.3-160 nM), S. hominis (MIC 160 nM), S. warneri (MIC 160 nM), E. faecalis (MIC 160 nM), including multidrug-resistant S. epidermidis strains causing biofilm-related infections (MIC 10-658 nM), S. aureus 1195 MRSA (MIC 160-329 nM), and vancomycin-resistant enterococci anti-VRE (MIC 82.3-329 nM).