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Peptide record

TPDB14623

Antibacterial Antifungal standard
68 amino acids
Basic Information
3D PDB MODEL
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TPDB14623
Antibacterial Antifungal
Anti-infective peptides
dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb
standard
No
A 68-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
LGSCVANKIKDEFFAMISISAIVKAAQKKAWKELAVTVLRFAKANGLKTNAIIVAGQLALWAVQCGLS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C330H545N87O87S3
HPY
A
7219.67
10.32
9
3
38
+6
0.04
0.622
119.26
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
11125
1.54
14
Residue Composition
number
13
A
1
R
3
N
1
D
2
C
2
E
3
Q
4
G
0
H
6
I
7
L
8
K
1
M
3
F
0
P
4
S
2
T
2
W
0
Y
6
V
Amino Acid Distribution
A: 13 R: 1 N: 3 D: 1 C: 2 E: 2 Q: 3 G: 4 H: 0 I: 6 L: 7 K: 8 M: 1 F: 3 P: 0 S: 4 T: 2 W: 2 Y: 0 V: 6
Chemical Descriptors
68 reviewed residue count
C330H545N87O87S3 sequence-only estimate (linear, free termini)
7219.67 sequence-only estimate (linear, free termini)
10.32 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
0.04 sequence-only estimate (linear, free termini)
0.622 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
A narrow-spectrum peptide with MIC in the range of nM. Active against L. sakei LMG 2313 or LMG 3354 or LMG 3355 or LMG 3356 or LMG 3357 (MIC 0.5-500 ng/ml), and L. plantarum LMG 2003 (MIC 31 ng/ml).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
A narrow-spectrum peptide with MIC in the range of nM. Active against L. sakei LMG 2313 or LMG 3354 or LMG 3355 or LMG 3356 or LMG 3357 (MIC 0.5-500 ng/ml), and L. plantarum LMG 2003 (MIC 31 ng/ml).