Peptide record

TPDB14618

Antibacterial Antifungal standard
64 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB14618
Antibacterial Antifungal
Anti-infective peptides
dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 64-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
LASTLGISTAAAKKAIDIIDAASTIASIISLIGIVTGAGAISYAIVATAKTMIKKYGKKYAAAW
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C293H492N72O84S1
RNCEQHFP
A
6399.62
10.23
7
2
38
+5
-0.43
0.850
125.47
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
9970
1.56
15
Residue Composition
number
16
A
0
R
0
N
2
D
0
C
0
E
0
Q
5
G
0
H
12
I
3
L
7
K
1
M
0
F
0
P
6
S
6
T
1
W
3
Y
2
V
Amino Acid Distribution
A: 16 R: 0 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 5 H: 0 I: 12 L: 3 K: 7 M: 1 F: 0 P: 0 S: 6 T: 6 W: 1 Y: 3 V: 2
Chemical Descriptors
64 reviewed residue count
C293H492N72O84S1 sequence-only estimate (linear, free termini)
6399.62 sequence-only estimate (linear, free termini)
10.23 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
-0.43 sequence-only estimate (linear, free termini)
0.850 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against Gram+ B. subtilis 168 or CU1065 or HB0042, B. brevis ATCC 8246, B. cereus ATCC 14579, C. michiganensis NCPPB382, B. licheniformis ATCC 9789, M. luteus, B. pumilus, B. sphaericus ATCC 14577, P. polymyxa, P. granivorans, B. megaterium 7A1, but not Arthrobacter sp., S.aureus, Gram- E.coli K-12, K.terrigena, Pseudomonas sp., and Erwinia spp. (e.g. E.carotovora) Updated Jan2026
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against Gram+ B. subtilis 168 or CU1065 or HB0042, B. brevis ATCC 8246, B. cereus ATCC 14579, C. michiganensis NCPPB382, B. licheniformis ATCC 9789, M. luteus, B. pumilus, B. sphaericus ATCC 14577, P. polymyxa, P. granivorans, B. megaterium 7A1, but not Arthrobacter sp., S.aureus, Gram- E.coli K-12, K.terrigena, Pseudomonas sp., and Erwinia spp. (e.g. E.carotovora) Updated Jan2026