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Peptide record

TPDB14576

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB14576
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF CAFPdb ToxinPred 3.0
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
KVFLGLK
Physicochemical Analysis
C40H69N9O8
ARNDCEQHIMPSTWY
LK
804.04
10.60
2
0
4
+2
-0.19
0.914
152.86
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
2
L
2
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C40H69N9O8
804.04
10.60
+2
-0.19
0.914
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
24-64 µg/mL

Target

S. pneumoniae ATCC 49619

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
e ATCC 51302, P. aeruginosa ATCC 27553, S. aureus ATCC 25923, B. subtilis ATCC 23631, and S. pneumoniae ATCC 49619 (MIC 24-64 ug/ml).
Evidence 2 Activity

Activity

MIC
Antifungal
24-64 µg/mL

Target

S. pneumoniae ATCC 49619

Source & Reference

dbAMP DRAMP CAFPdb

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
e ATCC 51302, P. aeruginosa ATCC 27553, S. aureus ATCC 25923, B. subtilis ATCC 23631, and S. pneumoniae ATCC 49619 (MIC 24-64 ug/ml).
Evidence 3 Activity

Activity

MIC
Antiparasitic
24-64 µg/mL

Target

S. pneumoniae ATCC 49619

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
e ATCC 51302, P. aeruginosa ATCC 27553, S. aureus ATCC 25923, B. subtilis ATCC 23631, and S. pneumoniae ATCC 49619 (MIC 24-64 ug/ml).
Evidence 4 Activity

Activity

MIC
Antiviral
24-64 µg/mL

Target

S. pneumoniae ATCC 49619

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
e ATCC 51302, P. aeruginosa ATCC 27553, S. aureus ATCC 25923, B. subtilis ATCC 23631, and S. pneumoniae ATCC 49619 (MIC 24-64 ug/ml).
Evidence 5 Activity

Activity

5±0.4% Hemolysis
Toxicity
375 µM
Hemolytic Cytotoxic
5±0.4% Hemolysis | 375 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial peptide KSL-W and analogues: Promising agents to control plant diseases. | Peptides | 2018