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Peptide record

TPDB14552

Antibacterial Antifungal standard
54 amino acids
Basic Information
3D PDB MODEL
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TPDB14552
Antibacterial Antifungal
Anti-infective peptides
dbAMP DRAMP Peptipedia AFP-GFuse Antifp Antifungipept
standard
No
A 54-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
KTYYGTNGVHCTKNSLWGKVRLKNMKYDQNTTYMGRLQDILLGWATGAFGKTFH
Physicochemical Analysis
C280H428N78O77S3
EP
GT
6215.13
10.19
10
2
20
+6
2.23
-0.646
57.78
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
16960
272.88
19
Residue Composition
number
2
A
2
R
4
N
2
D
1
C
0
E
2
Q
7
G
2
H
1
I
5
L
6
K
2
M
2
F
0
P
1
S
7
T
2
W
4
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 4 D: 2 C: 1 E: 0 Q: 2 G: 7 H: 2 I: 1 L: 5 K: 6 M: 2 F: 2 P: 0 S: 1 T: 7 W: 2 Y: 4 V: 2
Chemical Descriptors
54
C280H428N78O77S3
6215.13
10.19
+6
2.23
-0.646
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against C. jejuni. Stable to heat treatment at 95oC for 15 min. Stable at pH > 3 but unstable at pH >10. Sensitive to proteases. Animal model:chicken: Bacterial colonization is significantly reduced in the treated birds.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against C. jejuni. Stable to heat treatment at 95oC for 15 min. Stable at pH > 3 but unstable at pH >10. Sensitive to proteases. Animal model:chicken: Bacterial colonization is significantly reduced in the treated birds.