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Peptide record

TPDB14542

Antibacterial Antifungal standard
73 amino acids
Basic Information
3D PDB MODEL
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TPDB14542
Antibacterial Antifungal
Anti-infective peptides
dbAMP Peptipedia Antifungipept
standard
No
A 73-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
KSMQVPFSRCCFSFAEQEIPLRAILCYRNTSSICSNEGLIFKLKRGKEACALDTVGWVQRHRKMLRHCPSKRK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C370H604N114O99S8
R
8490.05
10.27
17
5
25
+10
2.25
-0.401
70.82
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
7365
0.87
21
Residue Composition
number
4
A
8
R
2
N
1
D
6
C
4
E
3
Q
3
G
2
H
4
I
6
L
7
K
2
M
4
F
3
P
7
S
2
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 4 R: 8 N: 2 D: 1 C: 6 E: 4 Q: 3 G: 3 H: 2 I: 4 L: 6 K: 7 M: 2 F: 4 P: 3 S: 7 T: 2 W: 1 Y: 1 V: 3
Chemical Descriptors
73 reviewed residue count
C370H604N114O99S8 sequence-only estimate (linear, free termini)
8490.05 sequence-only estimate (linear, free termini)
10.27 sequence-only estimate (linear, free termini)
+10 sequence-only estimate (linear, free termini)
2.25 sequence-only estimate (linear, free termini)
-0.401 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
At 10 ug/ml, it killed 88% E. coli and 37% S. aureus.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
At 10 ug/ml, it killed 88% E. coli and 37% S. aureus.