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Peptide record

TPDB14537

Antibacterial Antifungal Antiviral standard
57 amino acids
Basic Information
3D PDB MODEL
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TPDB14537
Antibacterial Antifungal Antiviral
Anti-infective peptides
dbAMP Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP 3.0
standard
No
A 57-aa standard natural multi-activity (Antibacterial, Antifungal, and Antiviral) peptide sequence curated from dbAMP, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
KRRPAKAWSGRRTRLCCHRVPSPNSTNLKGHHVRLCKPCKLEPEPRLWVVPGALPQV
Physicochemical Analysis
C286H473N97O70S4
DIMFY
RP
6518.75
11.69
16
2
16
+11
15.89
-0.754
71.75
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11250
172.58
12
Residue Composition
number
3
A
8
R
2
N
0
D
4
C
2
E
1
Q
3
G
3
H
0
I
6
L
5
K
0
M
0
F
8
P
3
S
2
T
2
W
0
Y
5
V
Amino Acid Distribution
A: 3 R: 8 N: 2 D: 0 C: 4 E: 2 Q: 1 G: 3 H: 3 I: 0 L: 6 K: 5 M: 0 F: 0 P: 8 S: 3 T: 2 W: 2 Y: 0 V: 5
Chemical Descriptors
57
C286H473N97O70S4
6518.75
11.69
+11
15.89
-0.754
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against Gram+ S. aureus ATCC 25923 (MEC 21.50 ug/ml), L.monocytogenes (ATCC 19115 (MEC >200 ug/ml), Actinomyce isolated from clinical specimens (MEC 12.33 ug/ml), Gram- E. Coli ATCC 25922 (MEC 73.32 ug/ml), P. aeruginosa PA01 (MEC 86.45 ug/ml), S. typhi RE88 (MEC 91.69 ug/ml), fungi C.albicans ATCC 10231 or CMCC(B) 98001 (MEC>200 ug/ml), A. niger ATCC 16404 (MEC 28.55 ug/ml), yeast ATCC 2601 (MEC>200 ug/ml), M. hominis clinical (MEC 4.77 ug/ml), and Lentivirus (MEC 16.50 ug/ml) and Adenovirus Ad5 (MEC >200 ug/ml). MEC: Minimum effective concentration, which is the lowest protein concentration at which visual effects were observed (e.g., growth inhibition, microbe aggregation, infection efficiency decrease).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against Gram+ S. aureus ATCC 25923 (MEC 21.50 ug/ml), L.monocytogenes (ATCC 19115 (MEC >200 ug/ml), Actinomyce isolated from clinical specimens (MEC 12.33 ug/ml), Gram- E. Coli ATCC 25922 (MEC 73.32 ug/ml), P. aeruginosa PA01 (MEC 86.45 ug/ml), S. typhi RE88 (MEC 91.69 ug/ml), fungi C.albicans ATCC 10231 or CMCC(B) 98001 (MEC>200 ug/ml), A. niger ATCC 16404 (MEC 28.55 ug/ml), yeast ATCC 2601 (MEC>200 ug/ml), M. hominis clinical (MEC 4.77 ug/ml), and Lentivirus (MEC 16.50 ug/ml) and Adenovirus Ad5 (MEC >200 ug/ml). MEC: Minimum effective concentration, which is the lowest protein concentration at which visual effects were observed (e.g., growth inhibition, microbe aggregation, infection efficiency decrease).
Evidence 3 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
active against Gram+ S. aureus ATCC 25923 (MEC 21.50 ug/ml), L.monocytogenes (ATCC 19115 (MEC >200 ug/ml), Actinomyce isolated from clinical specimens (MEC 12.33 ug/ml), Gram- E. Coli ATCC 25922 (MEC 73.32 ug/ml), P. aeruginosa PA01 (MEC 86.45 ug/ml), S. typhi RE88 (MEC 91.69 ug/ml), fungi C.albicans ATCC 10231 or CMCC(B) 98001 (MEC>200 ug/ml), A. niger ATCC 16404 (MEC 28.55 ug/ml), yeast ATCC 2601 (MEC>200 ug/ml), M. hominis clinical (MEC 4.77 ug/ml), and Lentivirus (MEC 16.50 ug/ml) and Adenovirus Ad5 (MEC >200 ug/ml). MEC: Minimum effective concentration, which is the lowest protein concentration at which visual effects were observed (e.g., growth inhibition, microbe aggregation, infection efficiency decrease).