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Peptide record

TPDB14525

Antibacterial Antifungal Antiviral standard
68 amino acids
Basic Information
3D PDB MODEL
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TPDB14525
Antibacterial Antifungal Antiviral
Anti-infective peptides
dbAMP Peptipedia Antifungipept
standard
No
A 68-aa standard natural multi-activity (Antibacterial, Antifungal, and Antiviral) peptide sequence curated from dbAMP, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
KPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNK
Physicochemical Analysis
C356H582N106O93S4
GM
LK
7963.43
10.27
15
4
27
+9
15.02
-0.413
97.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
8730
109.63
20
Residue Composition
number
5
A
5
R
7
N
1
D
4
C
3
E
3
Q
0
G
2
H
4
I
8
L
8
K
0
M
2
F
4
P
3
S
1
T
1
W
2
Y
5
V
Amino Acid Distribution
A: 5 R: 5 N: 7 D: 1 C: 4 E: 3 Q: 3 G: 0 H: 2 I: 4 L: 8 K: 8 M: 0 F: 2 P: 4 S: 3 T: 1 W: 1 Y: 2 V: 5
Chemical Descriptors
68
C356H582N106O93S4
7963.43
10.27
+9
15.02
-0.413
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
At 10 ug/ml, it killed 86% E. coli and 59% S. aureus. The CXCR4 chemokine receptor is excluisvely activated by CXCL12. This activation promotes chemotaxis in leukocytes, stem cells, and central nervous systems. CXCR4 is also involved in cancer metastasis and HIV replication (co-receptor for infection).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
At 10 ug/ml, it killed 86% E. coli and 59% S. aureus. The CXCR4 chemokine receptor is excluisvely activated by CXCL12. This activation promotes chemotaxis in leukocytes, stem cells, and central nervous systems. CXCR4 is also involved in cancer metastasis and HIV replication (co-receptor for infection).
Evidence 3 Activity

Activity

Antiviral

Source & Reference

NA

Other

At 10 ug/ml, it killed 86% E. coli and 59% S. aureus. The CXCR4 chemokine receptor is excluisvely activated by CXCL12. This activation promotes chemotaxis in leukocytes, stem cells, and central nervous systems. CXCR4 is also involved in cancer metastasis and HIV replication (co-receptor for infection).