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Peptide record

TPDB14515

Psyle C Antibacterial Anticancer Antifungal Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB14515
Psyle C
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept
standard
No
A 25-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
KLCGETCFKFKCYTPGCSCSYPFCK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C126H187N29O34S6
ARNDQHIMWV
C
2844.41
8.30
4
1
6
+3
0.71
-0.060
15.60
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
3355
1.18
12
Residue Composition
number
0
A
0
R
0
N
0
D
6
C
1
E
0
Q
2
G
0
H
0
I
1
L
4
K
0
M
3
F
2
P
2
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 6 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 4 M: 0 F: 3 P: 2 S: 2 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
25 reviewed residue count
C126H187N29O34S6 sequence-only estimate (linear, free termini)
2844.41 sequence-only estimate (linear, free termini)
8.30 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
0.71 sequence-only estimate (linear, free termini)
-0.060 sequence-only estimate (linear, free termini)
Free Activity
L Activity
Not Available Activity
Free Activity
Antibacterial Activity
Psychotria leptothyrsa Activity
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Anticancer assay: human lymphoma cell line U937-GTB (IC50 3.5 uM). Updated 7/2021 GW
Evidence 2 Activity

Activity

Not Available
Anticancer

Target

Not Available
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2010

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 3 Activity

Activity

Antifungal

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Anticancer assay: human lymphoma cell line U937-GTB (IC50 3.5 uM). Updated 7/2021 GW