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Peptide record

TPDB14449

Antibacterial Antifungal Antiviral Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB14449
Antibacterial Antifungal Antiviral Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP DRAMP Peptipedia Antifungipept AI4AVP dbAMP 3.0 DRAVP 2.0 APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
ILSYLWNGIKSIF
Physicochemical Analysis
C77H116N16O18
ARDCEQHMPTV
I
1553.86
9.74
1
0
8
+1
-4.29
0.946
150.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
6990
449.85
4
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
2
L
1
K
0
M
1
F
0
P
2
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 2 K: 1 M: 0 F: 1 P: 0 S: 2 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
13
C77H116N16O18
1553.86
9.74
+1
-4.29
0.946
Evidence Records 6 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against herpes simplex virus type 1 (HSV-1, EC50=0.41 uM). It also showed activity against intracellular herpes simplex virus type 1 (HSV-1) ( Hong et al., 2014 ). Updated 11/2023
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against herpes simplex virus type 1 (HSV-1, EC50=0.41 uM). It also showed activity against intracellular herpes simplex virus type 1 (HSV-1) ( Hong et al., 2014 ). Updated 11/2023
Evidence 3 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
Active against herpes simplex virus type 1 (HSV-1, EC50=0.41 uM). It also showed activity against intracellular herpes simplex virus type 1 (HSV-1) ( Hong et al., 2014 ). Updated 11/2023
Evidence 4 Activity

Activity

IC50
Toxicity
26.15±1.91 µM
Cytotoxic
IC50 | 26.15±1.91 | µM | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Inhibitory activity and mechanism of two scorpion venom peptides against herpes simplex virus type 1. | Antiviral Res | 2014
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
33.32 ± 0.96 µM
Hemolytic Cytotoxic
50% Hemolysis | 33.32 ± 0.96 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Inhibitory activity and mechanism of two scorpion venom peptides against herpes simplex virus type 1. | Antiviral Res | 2014
Evidence 6 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.