TPDB

3D PDB MODEL

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TPDB ID TPDB14428

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 245-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

ILGGHLDAKGSFPWQAKMVSRHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLYPNYSQIDIGLIKLKQKVPVNERVMPICLPSKDYAEVGRVGYVSGWGRNANFNFTDHLKYVMLPVADQYDCIKHYEGSTVPEKKTPKSPVGEQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEKDTWYAAGILSFDKSCGVAEYGVYVKATSIQDWVQKTIAEN

FASTA

>TPDB14428|Antibacterial|length=245
ILGGHLDAKGSFPWQAKMVSRHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLYPNYSQIDIGLIKLKQKVPVNERVMPICLPSKDYAEVGRVGYVSGWGRNANFNFTDHLKYVMLPVADQYDCIKHYEGSTVPEKKTPKSPVGEQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEKDTWYAAGILSFDKSCGVAEYGVYVKATSIQDWVQKTIAEN

Formula C1231H1903N319O364S9

Absent Amino Acids

Common Amino Acids K

Mass 27284.11

PI 6.42

Basic Residues 32

Acidic Residues 27

Hydrophobic Residues 101

Net Charge -2

Boman Index 46.36

Hydrophobicity -0.282

Aliphatic Index 83.96

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 47120

Absorbance 280nm 172.70

Polar Residues 69

number

19

A

4

R

12

N

13

D

5

C

14

E

10

Q

18

G

7

H

13

I

20

L

21

K

4

M

7

F

11

P

13

S

16

T

5

W

13

Y

20

V

Amino Acid Distribution

A: 19 R: 4 N: 12 D: 13 C: 5 E: 14 Q: 10 G: 18 H: 7 I: 13 L: 20 K: 21 M: 4 F: 7 P: 11 S: 13 T: 16 W: 5 Y: 13 V: 20

Length

245

Formula

C1231H1903N319O364S9

Mass

27284.11

PI

6.42

Net Charge

-2

Boman Index

46.36

Hydrophobicity

-0.282

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.