TPDB

3D PDB MODEL

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TPDB ID TPDB14419

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 245-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

IIGGSMDAKGSFPWQAKMISRHGLTTGATLISDQWLLTTAMRALGAVVTLLLWGQLFAVELGNDAMDFEDDSCPKPPEIANGYVEHLVRYRCRQFYRLRAEGDGVYTLNDEKQWMNTVAGEKLPECEAVCGKPKHPVDQVQRIIGGSMDAKGSFPWQAKMISRHGLTTGATLISDQWLLTTAKNLFLNHSETASGKDIAPTLTLYVGKNQLVEIEKVILHPNHSVVDIGLIKLKQRVLVTERVMP

FASTA

>TPDB14419|Antibacterial|length=245
IIGGSMDAKGSFPWQAKMISRHGLTTGATLISDQWLLTTAMRALGAVVTLLLWGQLFAVELGNDAMDFEDDSCPKPPEIANGYVEHLVRYRCRQFYRLRAEGDGVYTLNDEKQWMNTVAGEKLPECEAVCGKPKHPVDQVQRIIGGSMDAKGSFPWQAKMISRHGLTTGATLISDQWLLTTAKNLFLNHSETASGKDIAPTLTLYVGKNQLVEIEKVILHPNHSVVDIGLIKLKQRVLVTERVMP

Formula C1210H1928N332O351S12

Absent Amino Acids

Common Amino Acids L

Mass 27127.35

PI 7.29

Basic Residues 33

Acidic Residues 26

Hydrophobic Residues 102

Net Charge +0

Boman Index 44.93

Hydrophobicity -0.129

Aliphatic Index 93.92

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 40700

Absorbance 280nm 150.03

Polar Residues 57

number

18

A

11

R

8

N

13

D

4

C

13

E

11

Q

21

G

7

H

14

I

27

L

15

K

8

M

6

F

11

P

12

S

17

T

6

W

5

Y

18

V

Amino Acid Distribution

A: 18 R: 11 N: 8 D: 13 C: 4 E: 13 Q: 11 G: 21 H: 7 I: 14 L: 27 K: 15 M: 8 F: 6 P: 11 S: 12 T: 17 W: 6 Y: 5 V: 18

Length

245

Formula

C1210H1928N332O351S12

Mass

27127.35

PI

7.29

Net Charge

+0

Boman Index

44.93

Hydrophobicity

-0.129

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.