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Peptide record

TPDB14387

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
75 amino acids
Basic Information
3D PDB MODEL
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TPDB14387
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP DRAMP Peptipedia Antifungipept dbAMP 3.0 i2APP
standard
No
A 75-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GWINEEKIQKKIDERMGNTVLGGMAKAIVHKMAKNEFQCMANMDMLGNCEKHCQTSGEKGYCHGTKCKCGTPLSY
Physicochemical Analysis
C352H569N103O108S12
K
8356.74
8.30
14
8
23
+3
22.23
-0.640
49.47
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
8855
105.96
22
Residue Composition
number
4
A
1
R
5
N
2
D
6
C
6
E
3
Q
9
G
3
H
4
I
3
L
10
K
6
M
1
F
1
P
2
S
4
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 4 R: 1 N: 5 D: 2 C: 6 E: 6 Q: 3 G: 9 H: 3 I: 4 L: 3 K: 10 M: 6 F: 1 P: 1 S: 2 T: 4 W: 1 Y: 2 V: 2
Chemical Descriptors
75
C352H569N103O108S12
8356.74
8.30
+3
22.23
-0.640
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against B. subtilis (MIC 1 uM), K. pneumoniae (MIC ~10 uM). Recombinant form also produced 98% mortality in sexual stage
Evidence 2 Activity

Activity

MIC
Antifungal
1 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against B. subtilis (MIC 1 uM), K. pneumoniae (MIC ~10 uM). Recombinant form also produced 98% mortality in sexual stage
Evidence 3 Activity

Activity

MIC
Antiparasitic
1 µM

Target

B. subtilis

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against B. subtilis (MIC 1 uM), K. pneumoniae (MIC ~10 uM). Recombinant form also produced 98% mortality in sexual stage