Back to search

Peptide record

TPDB14374

Antibacterial Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB14374
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP Peptipedia
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from dbAMP and Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
GVCRXVCRRGVCRXVCRR
Physicochemical Analysis
C72H136N34O17S4
ANDEQHILKMFPSTWY
R
1878.33
11.71
6
0
4
+6
4.20
-0.056
64.44
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
250
13.31
4
Residue Composition
number
0
A
6
R
0
N
0
D
4
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
18
C72H136N34O17S4
1878.33
11.71
+6
4.20
-0.056
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The cyclic cystine ladder in ?-defensins is important for structure and stability, but not antibacterial activity. | J Biol Chem | 2013