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Peptide record

TPDB14360

Viphi E Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB14360
Viphi E
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
GSIPCGESCVFIPCISAVIGCSCSNKVCYKN
Physicochemical Analysis
C134H217N35O42S6
RDQHLMTW
C
3182.77
7.62
2
1
10
+1
1.71
0.716
81.61
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
58.60
14
Residue Composition
number
1
A
0
R
2
N
0
D
6
C
1
E
0
Q
3
G
0
H
4
I
0
L
2
K
0
M
1
F
2
P
5
S
0
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 0 C: 6 E: 1 Q: 0 G: 3 H: 0 I: 4 L: 0 K: 2 M: 0 F: 1 P: 2 S: 5 T: 0 W: 0 Y: 1 V: 3
Chemical Descriptors
31
C134H217N35O42S6
3182.77
7.62
+1
1.71
0.716
Free
L
Not Available
Free
Antibacterial
Viola philippica
Evidence Records 3 records
Evidence 1 Activity

Activity

Not Available
Anticancer

Target

Not Available
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
Toxicity
1.55±0.09 µM
Cytotoxic
IC50 | 1.55±0.09 | µM | target cell: Human foreskin fibroblasts (HFF)

Target

Human foreskin fibroblasts (HFF)

Source & Reference

NA
DBAASP
Isolation and characterization of cytotoxic cyclotides from Viola philippica. | Peptides | 2011
Evidence 3 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.