Back to search

Peptide record

TPDB14359

Viphi F Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
31 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB14359
Viphi F
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 31-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
GSIPCGESCVFIPCISAIIGCSCSSKVCYKN
Physicochemical Analysis
C134H218N34O42S6
RDQHLMTW
CS
3169.77
7.62
2
1
10
+1
1.04
0.813
84.84
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
58.84
14
Residue Composition
number
1
A
0
R
1
N
0
D
6
C
1
E
0
Q
3
G
0
H
5
I
0
L
2
K
0
M
1
F
2
P
6
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 6 E: 1 Q: 0 G: 3 H: 0 I: 5 L: 0 K: 2 M: 0 F: 1 P: 2 S: 6 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
31
C134H218N34O42S6
3169.77
7.62
+1
1.04
0.813
Free
L
Not Available
Free
Antibacterial
Viola philippica
Evidence Records 3 records
Evidence 1 Activity

Activity

Not Available
Anticancer

Target

Not Available
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
Toxicity
1.76±0.12 µM
Cytotoxic
IC50 | 1.76±0.12 | µM | target cell: Human foreskin fibroblasts (HFF)

Target

Human foreskin fibroblasts (HFF)

Source & Reference

NA
DBAASP
Isolation and characterization of cytotoxic cyclotides from Viola philippica. | Peptides | 2011
Evidence 3 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.