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Peptide record

TPDB14320

Antibacterial Antifungal standard
103 amino acids
Basic Information
3D PDB MODEL
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TPDB14320
Antibacterial Antifungal
Anti-infective peptides
dbAMP Peptipedia Antifungipept
standard
No
A 103-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
GNANSNYEGGGSRSRNTGARNSLGRNAPTHIYSDPSTVKCANAVFSGMVGGAIKGGPVGMTRGTIGGAVIGQCLSGGGNGNGGGNRAGSSNCSGSNVGGTCSR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C393H643N141O142S6
W
G
9807.65
10.36
10
2
25
+7
1.69
-0.447
47.38
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3230
0.33
38
Residue Composition
number
8
A
7
R
12
N
1
D
4
C
1
E
1
Q
27
G
1
H
4
I
2
L
2
K
2
M
1
F
3
P
13
S
6
T
0
W
2
Y
6
V
Amino Acid Distribution
A: 8 R: 7 N: 12 D: 1 C: 4 E: 1 Q: 1 G: 27 H: 1 I: 4 L: 2 K: 2 M: 2 F: 1 P: 3 S: 13 T: 6 W: 0 Y: 2 V: 6
Chemical Descriptors
103 reviewed residue count
C393H643N141O142S6 sequence-only estimate (linear, free termini)
9807.65 sequence-only estimate (linear, free termini)
10.36 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
1.69 sequence-only estimate (linear, free termini)
-0.447 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Expression of this peptide in a plasma-transformed E. coli inhibited its growth. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Expression of this peptide in a plasma-transformed E. coli inhibited its growth. Updated 7/2021