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Peptide record

TPDB14303

Viba17 Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB14303
Viba17
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifp Antifungipept APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
GLPVCGETCVGGTCNTPGCGCSWPVCTRN
Physicochemical Analysis
C115H183N35O39S6
ADQHIKMFY
CG
2872.29
5.90
1
1
5
-0
2.13
0.162
43.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
204.54
13
Residue Composition
number
0
A
1
R
2
N
0
D
6
C
1
E
0
Q
6
G
0
H
0
I
1
L
0
K
0
M
0
F
3
P
1
S
4
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 0 C: 6 E: 1 Q: 0 G: 6 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 3 S: 1 T: 4 W: 1 Y: 0 V: 3
Chemical Descriptors
29
C115H183N35O39S6
2872.29
5.90
-0
2.13
0.162
Free
L
Not Available
Free
Antibacterial
Viola philippica
Evidence Records 3 records
Evidence 1 Activity

Activity

Not Available
Anticancer

Target

Not Available
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
Toxicity
2.38±0.09 µM
Cytotoxic
IC50 | 2.38±0.09 | µM | target cell: Human foreskin fibroblasts (HFF)

Target

Human foreskin fibroblasts (HFF)

Source & Reference

NA
DBAASP
Isolation and characterization of cytotoxic cyclotides from Viola philippica. | Peptides | 2011
Evidence 3 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.