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Peptide record

TPDB14302

Viba 15 Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB14302
Viba 15
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
GLPVCGETCVGGTCNTPGCACSWPVCTRN
Physicochemical Analysis
C116H185N35O39S6
DQHIKMFY
C
2886.32
5.90
1
1
6
-0
1.95
0.238
46.90
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5875
203.55
13
Residue Composition
number
1
A
1
R
2
N
0
D
6
C
1
E
0
Q
5
G
0
H
0
I
1
L
0
K
0
M
0
F
3
P
1
S
4
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 1 N: 2 D: 0 C: 6 E: 1 Q: 0 G: 5 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 3 S: 1 T: 4 W: 1 Y: 0 V: 3
Chemical Descriptors
29
C116H185N35O39S6
2886.32
5.90
-0
1.95
0.238
Free
L
Not Available
Free
Antibacterial
Viola philippica
Evidence Records 3 records
Evidence 1 Activity

Activity

Not Available
Anticancer

Target

Not Available
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
Toxicity
2.38±0.09 µM
Cytotoxic
IC50 | 2.38±0.09 | µM | target cell: Human foreskin fibroblasts (HFF)

Target

Human foreskin fibroblasts (HFF)

Source & Reference

NA
DBAASP
Isolation and characterization of cytotoxic cyclotides from Viola philippica. | Peptides | 2011
Evidence 3 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.