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Peptide record

TPDB14300

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
33 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB14300
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb AI4AVP dbAMP 3.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GLMDSLKGLAATAGKTVLQGLLKTASCKLEKTC
Physicochemical Analysis
C144H257N39O45S3
RNHIFPWY
L
3351.04
9.65
5
2
13
+3
4.40
0.270
103.64
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.73
9
Residue Composition
number
4
A
0
R
0
N
1
D
2
C
1
E
1
Q
4
G
0
H
0
I
7
L
5
K
1
M
0
F
0
P
2
S
4
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 1 C: 2 E: 1 Q: 1 G: 4 H: 0 I: 0 L: 7 K: 5 M: 1 F: 0 P: 0 S: 2 T: 4 W: 0 Y: 0 V: 1
Chemical Descriptors
33
C144H257N39O45S3
3351.04
9.65
+3
4.40
0.270
Evidence Records 32 records
Evidence 1 Activity

Activity

MIC
Antibacterial
12.5 ug/mL

Target

V. vulnificus

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
The peptide activity has been determined ( Fan et al., 2022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.
Evidence 2 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

P. mirabilis

Source & Reference

dbAMP DRAMP

Other

een determined ( Fan et al., 2022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

S. enterica

Source & Reference

dbAMP DRAMP

Other

022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S
Evidence 4 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

S. sonnei

Source & Reference

dbAMP DRAMP

Other

. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S.
Evidence 5 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

A.hydrophila

Source & Reference

dbAMP DRAMP

Other

L), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L
Evidence 6 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP DRAMP

Other

l), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 10
Evidence 7 Activity

Activity

MIC
Antibacterial
100 ug/mL

Target

S. iniae

Source & Reference

dbAMP DRAMP

Other

), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 100 ug/ml). Scrash healing and che
Evidence 8 Activity

Activity

MIC
Antibacterial
25 ug/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP

Other

l), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 100 ug/ml). Scrash healing and chemotactic activity were observed
Evidence 9 Activity

Activity

MIC
Antifungal
12.5 ug/mL

Target

V. vulnificus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
The peptide activity has been determined ( Fan et al., 2022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.
Evidence 10 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

P. mirabilis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

een determined ( Fan et al., 2022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.
Evidence 11 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

S. enterica

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S
Evidence 12 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

S. sonnei

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S.
Evidence 13 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

A.hydrophila

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

L), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L
Evidence 14 Activity

Activity

MIC
Antifungal
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

l), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 10
Evidence 15 Activity

Activity

MIC
Antifungal
100 ug/mL

Target

S. iniae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 100 ug/ml). Scrash healing and che
Evidence 16 Activity

Activity

MIC
Antifungal
25 ug/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

l), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 100 ug/ml). Scrash healing and chemotactic activity were observed
Evidence 17 Activity

Activity

MIC
Antiparasitic
12.5 ug/mL

Target

V. vulnificus

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
The peptide activity has been determined ( Fan et al., 2022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.
Evidence 18 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

P. mirabilis

Source & Reference

dbAMP 3.0 DRAMP

Other

een determined ( Fan et al., 2022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.
Evidence 19 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

S. enterica

Source & Reference

dbAMP 3.0 DRAMP

Other

022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S
Evidence 20 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

S. sonnei

Source & Reference

dbAMP 3.0 DRAMP

Other

. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S.
Evidence 21 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

A.hydrophila

Source & Reference

dbAMP 3.0 DRAMP

Other

L), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L
Evidence 22 Activity

Activity

MIC
Antiparasitic
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP 3.0 DRAMP

Other

l), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 10
Evidence 23 Activity

Activity

MIC
Antiparasitic
100 ug/mL

Target

S. iniae

Source & Reference

dbAMP 3.0 DRAMP

Other

), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 100 ug/ml). Scrash healing and che
Evidence 24 Activity

Activity

MIC
Antiparasitic
25 ug/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP 3.0 DRAMP

Other

l), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 100 ug/ml). Scrash healing and chemotactic activity were observed
Evidence 25 Activity

Activity

MIC
Antiviral
12.5 ug/mL

Target

V. vulnificus

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
The peptide activity has been determined ( Fan et al., 2022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.
Evidence 26 Activity

Activity

MIC
Antiviral
100 µg/mL

Target

P. mirabilis

Source & Reference

dbAMP 3.0 DRAMP

Other

een determined ( Fan et al., 2022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.
Evidence 27 Activity

Activity

MIC
Antiviral
100 µg/mL

Target

S. enterica

Source & Reference

dbAMP 3.0 DRAMP

Other

022 ). Active against Gram- V. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S
Evidence 28 Activity

Activity

MIC
Antiviral
100 µg/mL

Target

S. sonnei

Source & Reference

dbAMP 3.0 DRAMP

Other

. vulnificus (MIC 12.5 ug/mL), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S.
Evidence 29 Activity

Activity

MIC
Antiviral
>100 µg/mL

Target

A.hydrophila

Source & Reference

dbAMP 3.0 DRAMP

Other

L), P. mirabilis (MIC 100 ug/ml), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L
Evidence 30 Activity

Activity

MIC
Antiviral
>100 µg/mL

Target

E.coli

Source & Reference

dbAMP 3.0 DRAMP

Other

l), S. enterica (MIC 100 ug/ml), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 10
Evidence 31 Activity

Activity

MIC
Antiviral
100 ug/mL

Target

S. iniae

Source & Reference

dbAMP 3.0 DRAMP

Other

), S. sonnei (MIC 100 ug/ml), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 100 ug/ml). Scrash healing and che
Evidence 32 Activity

Activity

MIC
Antiviral
25 ug/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP 3.0 DRAMP

Other

l), A.hydrophila (MIC>100 ug/ml), E.coli (MIC>100 ug/ml), Gram+ S. iniae (MIC 100 ug/mL), S. epidermidis (MIC 25 ug/mL), L.monocytogenes (MIC > 100 ug/ml). Scrash healing and chemotactic activity were observed