Peptide record

TPDB14262

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB14262
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb AI4AVP dbAMP 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GILTDTLKGAAKNVAGVLLDKLKCKITGGC
Physicochemical Analysis
C131H234N36O39S2
REQHMFPSWY
GLK
3001.64
9.65
5
2
12
+3
4.03
0.423
120.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.16
6
Residue Composition
number
3
A
0
R
1
N
2
D
2
C
0
E
0
Q
5
G
0
H
2
I
5
L
5
K
0
M
0
F
0
P
0
S
3
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 1 D: 2 C: 2 E: 0 Q: 0 G: 5 H: 0 I: 2 L: 5 K: 5 M: 0 F: 0 P: 0 S: 0 T: 3 W: 0 Y: 0 V: 2
Chemical Descriptors
30
C131H234N36O39S2
3001.64
9.65
+3
4.03
0.423
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8-16 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 202
Evidence 2 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.enteritidis

Source & Reference

dbAMP DRAMP

Other

active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 2022 ).
Evidence 3 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

dbAMP DRAMP

Other

active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 2022 ).
Evidence 4 Activity

Activity

MIC
Antifungal
8-16 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 202
Evidence 5 Activity

Activity

MIC
Antifungal
128 µg/mL

Target

S.enteritidis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 2022 ).
Evidence 6 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 2022 ).
Evidence 7 Activity

Activity

MIC
Antiparasitic
8-16 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 202
Evidence 8 Activity

Activity

MIC
Antiparasitic
128 µg/mL

Target

S.enteritidis

Source & Reference

dbAMP 3.0 DRAMP

Other

active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 2022 ).
Evidence 9 Activity

Activity

MIC
Antiparasitic
64 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

dbAMP 3.0 DRAMP

Other

active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 2022 ).
Evidence 10 Activity

Activity

MIC
Antiviral
8-16 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 202
Evidence 11 Activity

Activity

MIC
Antiviral
128 µg/mL

Target

S.enteritidis

Source & Reference

dbAMP 3.0 DRAMP

Other

active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 2022 ).
Evidence 12 Activity

Activity

MIC
Antiviral
64 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

dbAMP 3.0 DRAMP

Other

active against E. coli ATCC 25922 (MIC 8-16 ug/ml), S.enteritidis (MIC 128 ug/ml), and S. aureus ATCC 29213 (MIC 64 ug/ml) ( Lin et al., 2022 ).
Evidence 13 Activity

Activity

50% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP