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Peptide record

TPDB14260

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB14260
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP DRAMP Peptipedia Antifungipept CAFPdb AI4AVP dbAMP 3.0
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GILLNTLKGAAKNVAGVLLDKLKCKITGGC
Physicochemical Analysis
C133H239N37O37S2
REQHMFPSWY
L
3012.71
10.06
5
1
13
+4
2.52
0.573
133.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
4.15
6
Residue Composition
number
3
A
0
R
2
N
1
D
2
C
0
E
0
Q
5
G
0
H
2
I
6
L
5
K
0
M
0
F
0
P
0
S
2
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 2 D: 1 C: 2 E: 0 Q: 0 G: 5 H: 0 I: 2 L: 6 K: 5 M: 0 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 2
Chemical Descriptors
30
C133H239N37O37S2
3012.71
10.06
+4
2.52
0.573
Evidence Records 13 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al.
Evidence 2 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

S. enteritidis

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al., 2022 ).
Evidence 3 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al., 2022 ).
Evidence 4 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al.
Evidence 5 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

S. enteritidis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al., 2022 ).
Evidence 6 Activity

Activity

MIC
Antifungal
4-8 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al., 2022 ).
Evidence 7 Activity

Activity

MIC
Antiparasitic
8 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.
Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al.
Evidence 8 Activity

Activity

MIC
Antiparasitic
64 µg/mL

Target

S. enteritidis

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al., 2022 ).
Evidence 9 Activity

Activity

MIC
Antiparasitic
4-8 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al., 2022 ).
Evidence 10 Activity

Activity

MIC
Antiviral
8 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.
Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al.
Evidence 11 Activity

Activity

MIC
Antiviral
64 µg/mL

Target

S. enteritidis

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al., 2022 ).
Evidence 12 Activity

Activity

MIC
Antiviral
4-8 µg/mL

Target

Staphylococcus aureus ATCC 29213

Source & Reference

dbAMP 3.0 DRAMP

Other

Active against E. coli ATCC 25922 (MIC 8 ug/ml), S. enteritidis (MIC 64 ug/ml), and S. aureus ATCC 29213 (MIC 4-8 ug/ml) ( Richter et al., 2022 ).
Evidence 13 Activity

Activity

50% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP
Associating Biological Activity and Predicted Structure of Antimicrobial Peptides from Amphibians and Insects | Antibiotics (Basel) | 2022