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Peptide record

TPDB14247

Psyle A Antibacterial Anticancer Antifungal Antiviral Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB14247
Psyle A
Antibacterial Anticancer Antifungal Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
dbAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF pep-lab Antifungipept
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
GIACGESCVFLGCFIPGCSCKSKVCYFN
Physicochemical Analysis
C128H195N31O36S6
RDQHMTW
C
2936.50
7.62
2
1
10
+1
-1.68
0.882
66.07
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1865
63.51
11
Residue Composition
number
1
A
0
R
1
N
0
D
6
C
1
E
0
Q
4
G
0
H
2
I
1
L
2
K
0
M
3
F
1
P
3
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 6 E: 1 Q: 0 G: 4 H: 0 I: 2 L: 1 K: 2 M: 0 F: 3 P: 1 S: 3 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
28
C128H195N31O36S6
2936.50
7.62
+1
-1.68
0.882
Free
L
Not Available
Free
Antibacterial
Psychotria leptothyrsa
Evidence Records 2 records
Evidence 1 Activity

Activity

Not Available
Anticancer

Target

Not Available
Not Available
Not Available

Assay & Model

Not Available
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2010

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
Toxicity
26 µM
Cytotoxic
Cytotoxicity: [Ref.20575512] Cytotoxicity: the human lymphoma cell line U-937 GTB (IC50 = 26 µM).

Source & Reference

NA
DRAMP
J Nat Prod. 2010 Jul 23 73(7):1207-1213.