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Peptide record

TPDB14245

Antibacterial Antifungal Toxicity standard
53 amino acids
Basic Information
3D PDB MODEL
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TPDB14245
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 53-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GHLGRPYIGGGGGFNRGGGFHRGGGFHRGGGFHSGGGFHRGGGFHSGGSFGYR
Physicochemical Analysis
C233H322N84O60
ADCEQKMTWV
G
5259.65
12.40
12
0
11
+7
1.47
-0.725
14.72
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
2980
56.66
6
Residue Composition
number
0
A
6
R
1
N
0
D
0
C
0
E
0
Q
25
G
6
H
1
I
1
L
0
K
0
M
7
F
1
P
3
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 25 H: 6 I: 1 L: 1 K: 0 M: 0 F: 7 P: 1 S: 3 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
53
C233H322N84O60
5259.65
12.40
+7
1.47
-0.725
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against B. megaterium (MIC 0.5–1.25 uM). A variant has been found (see AP2742 ). Updated 10/2016.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against B. megaterium (MIC 0.5–1.25 uM). A variant has been found (see AP2742 ). Updated 10/2016.
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Armadillidin H, a Glycine-Rich Peptide from the Terrestrial Crustacean Armadillidium vulgare, Displays an Unexpected Wide Antimicrobial Spectrum with Membranolytic Activity. | Front Microbiol | 2016