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Peptide record

TPDB14231

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
60 amino acids
Basic Information
3D PDB MODEL
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TPDB14231
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia Antifp Antifungipept AVPpred-BWR
standard
No
A 60-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GGAPATSANAAGAAAIVGALAGIPGGPLGVVVGAVSAGLTTGIGSTVGSGSASSSAGGGS
Physicochemical Analysis
C204H343N61O75
RDCEQHKMFWY
G
4850.33
6.02
0
0
26
-0
-0.90
0.837
91.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
14
Residue Composition
number
14
A
0
R
1
N
0
D
0
C
0
E
0
Q
17
G
0
H
3
I
3
L
0
K
0
M
0
F
3
P
9
S
4
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 14 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 17 H: 0 I: 3 L: 3 K: 0 M: 0 F: 0 P: 3 S: 9 T: 4 W: 0 Y: 0 V: 6
Chemical Descriptors
60
C204H343N61O75
4850.33
6.02
-0
-0.90
0.837
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
1.1-5.3 µM

Target

Escherichia coli ATCC 25922 or BAA-196 or DH5alpha

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
Active against E. coli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mir
Evidence 2 Activity

Activity

MIC
Antibacterial
6.3-12.7 µM

Target

S. typhimurium

Source & Reference

dbAMP DRAMP

Other

Active against E. coli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al
Evidence 3 Activity

Activity

MIC
Antibacterial
2.4-4.4 µM

Target

S. flexneri 2457T or M90T

Source & Reference

dbAMP DRAMP

Other

oli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al., 2020 ). Anticancer: inhibited MDA-MB-231
Evidence 4 Activity

Activity

MIC
Antibacterial
5.3 µM

Target

P. mirabilis

Source & Reference

dbAMP DRAMP

Other

.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al., 2020 ). Anticancer: inhibited MDA-MB-231 breast cancer cells.
Evidence 5 Activity

Activity

MIC
Antifungal
1.1-5.3 µM

Target

Escherichia coli ATCC 25922 or BAA-196 or DH5alpha

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
Active against E. coli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mir
Evidence 6 Activity

Activity

MIC
Antifungal
6.3-12.7 µM

Target

S. typhimurium

Source & Reference

dbAMP DRAMP Antifungipept

Other

Active against E. coli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al
Evidence 7 Activity

Activity

MIC
Antifungal
2.4-4.4 µM

Target

S. flexneri 2457T or M90T

Source & Reference

dbAMP DRAMP Antifungipept

Other

oli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al., 2020 ). Anticancer: inhibited MDA-MB-231
Evidence 8 Activity

Activity

MIC
Antifungal
5.3 µM

Target

P. mirabilis

Source & Reference

dbAMP DRAMP Antifungipept

Other

.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al., 2020 ). Anticancer: inhibited MDA-MB-231 breast cancer cells.
Evidence 9 Activity

Activity

MIC
Antiparasitic
1.1-5.3 µM

Target

Escherichia coli ATCC 25922 or BAA-196 or DH5alpha

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
Active against E. coli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mir
Evidence 10 Activity

Activity

MIC
Antiparasitic
6.3-12.7 µM

Target

S. typhimurium

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al
Evidence 11 Activity

Activity

MIC
Antiparasitic
2.4-4.4 µM

Target

S. flexneri 2457T or M90T

Source & Reference

DRAMP

Other

oli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al., 2020 ). Anticancer: inhibited MDA-MB-231
Evidence 12 Activity

Activity

MIC
Antiparasitic
5.3 µM

Target

P. mirabilis

Source & Reference

DRAMP

Other

.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al., 2020 ). Anticancer: inhibited MDA-MB-231 breast cancer cells.
Evidence 13 Activity

Activity

MIC
Antiviral
1.1-5.3 µM

Target

Escherichia coli ATCC 25922 or BAA-196 or DH5alpha

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
Active against E. coli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mir
Evidence 14 Activity

Activity

MIC
Antiviral
6.3-12.7 µM

Target

S. typhimurium

Source & Reference

DRAMP

Other

Active against E. coli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al
Evidence 15 Activity

Activity

MIC
Antiviral
2.4-4.4 µM

Target

S. flexneri 2457T or M90T

Source & Reference

DRAMP

Other

oli ATCC 25922 or BAA-196 or DH5alpha (MIC 1.1-5.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al., 2020 ). Anticancer: inhibited MDA-MB-231
Evidence 16 Activity

Activity

MIC
Antiviral
5.3 µM

Target

P. mirabilis

Source & Reference

DRAMP

Other

.3 uM), S. typhimurium (MIC 6.3-12.7 uM), S. flexneri 2457T or M90T (MIC 2.4-4.4 uM), and P. mirabilis (MIC 5.3 uM) ( Palmer et al., 2020 ). Anticancer: inhibited MDA-MB-231 breast cancer cells.