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Peptide record

TPDB14198

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
84 amino acids
Basic Information
3D PDB MODEL
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TPDB14198
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia ACP740 _ACP240 dbACP AFP-GFuse Antifp Antifungipept
standard
No
A 84-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GETDPNTQLLNDLGNNMAWGAALGAPGGLGSAALGAAGGALQTVGQGLIDHGPVNVFIPVLIGPSWNGSGSGYNSATSSSGSGS
Physicochemical Analysis
C342H532N98O118S1
RCK
G
7936.63
3.50
1
4
31
-4
2.26
0.065
81.43
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12490
157.37
25
Residue Composition
number
10
A
0
R
7
N
3
D
0
C
1
E
3
Q
19
G
1
H
3
I
9
L
0
K
1
M
1
F
5
P
10
S
4
T
2
W
1
Y
4
V
Amino Acid Distribution
A: 10 R: 0 N: 7 D: 3 C: 0 E: 1 Q: 3 G: 19 H: 1 I: 3 L: 9 K: 0 M: 1 F: 1 P: 5 S: 10 T: 4 W: 2 Y: 1 V: 4
Chemical Descriptors
84
C342H532N98O118S1
7936.63
3.50
-4
2.26
0.065
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli RYC1000, E. coli B, E. coli F., E. coli ML35p, S. enterica Enteritidis, S. enterica Typhimurium, E. cloacae and K. pneumoniae ( Vassiliadis G et al. 2010 ). The peptide lost its activity by amyloid formation (i.e. aggregates) (Bieler S et al 2005 JBC 280:26880).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli RYC1000, E. coli B, E. coli F., E. coli ML35p, S. enterica Enteritidis, S. enterica Typhimurium, E. cloacae and K. pneumoniae ( Vassiliadis G et al. 2010 ). The peptide lost its activity by amyloid formation (i.e. aggregates) (Bieler S et al 2005 JBC 280:26880).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against E. coli RYC1000, E. coli B, E. coli F., E. coli ML35p, S. enterica Enteritidis, S. enterica Typhimurium, E. cloacae and K. pneumoniae ( Vassiliadis G et al. 2010 ). The peptide lost its activity by amyloid formation (i.e. aggregates) (Bieler S et al 2005 JBC 280:26880).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

DRAMP

Other

Active against E. coli RYC1000, E. coli B, E. coli F., E. coli ML35p, S. enterica Enteritidis, S. enterica Typhimurium, E. cloacae and K. pneumoniae ( Vassiliadis G et al. 2010 ). The peptide lost its activity by amyloid formation (i.e. aggregates) (Bieler S et al 2005 JBC 280:26880).